Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  5
• Reference
  J:164460 Su Z, et al., Untangling HDL quantitative trait loci on mouse chromosome 5 and identifying Scarb1 and Acads as the underlying genes. J Lipid Res. 2010 Sep;51(9):2706-13
• ID
  MGI:4887475

Genes

Gene	Description
Scarb1
Acads	rs3668084

Notes

• Experiment
  Authors use the diiferences in protein function and expression levels of Scarb1 between C57Bl/6, CAST, NZB, SM, NZO and SJL to conclude that Scarb1 is a likely candidate for Hdlq1 in mouse Chromosome 5.
  
  In addition Hdlq1 was confirmed as distinct from Hdlq8 using the NZB X NZW intercross. The peak of Hdlq8 was refined using SNP rs3668084 to a position of 116 Mb (LOD 12.7) at approximately 60 cM within a 95% confidence range of 107 to 117 Mb. Acads , a marker within this range was suggested as the gene underlying the Hdlq8 phenotype