Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  14
• Reference
  J:167733 Grizenkova J, et al., The retinoic acid receptor beta (Rarb) region of Mmu14 is associated with prion disease incubation time in mouse. PLoS One. 2010;5(12):e15019
• ID
  MGI:4936836

Genes

Gene	Description
Prdt6
Rarb	rs48898775
Thrb	rs16822230

Notes

• Experiment
  A locus on mouse Chromosome 14 was shown as displaying an association with prion disease susceptibility incubation as indicated using Northport heterogeneous stock (HS)animals.This HS stock was derived from semi-randomly mated parental inbred strains A/J,AKR/J, BALB/cJ, C3H/HeJ, C57BL/6J, CBA/J, DBA/2J LP/J. Strain distribution patterns of the aformentioned strains indicated that a QTL region containing Prdt6 was associated with Rarb (rs48898775 exon 3, Allele test p value = .0002) and Thrb (rs16822230 Exon 6,Allele test p-value = .0005)