Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  1
• Reference
  J:175511 Hageman RS, et al., Uncovering genes and regulatory pathways related to urinary albumin excretion. J Am Soc Nephrol. 2011 Jan;22(1):73-81
• ID
  MGI:5637831

Genes

Gene	Assay Type
Albq10	susceptibility/resistance

Notes

• Experiment
  Linkage analysis was performed on 371 male (MRL/MpJ x SM/J)F2 intercross animals using 258 SNP markers to identify QTL associated with increased urinary albumin-to-creatinine ratio (ACR). Parental strain SM/J exhibits higher ACR values when compared to MRL/MpJ.
  
  QTL Albq10 maps to 35.3 - 124.2 Mb on Chromosome 1 with a peak LOD score of 4.1 at 46 cM in linkage with urinary ACR. SM/J alleles confer increased susceptibility to increased ACR values.