Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  11
• Reference
  J:208464 Kayashima Y, et al., Quantitative trait loci affecting atherosclerosis at the aortic root identified in an intercross between DBA2J and 129S6 apolipoprotein E-null mice. PLoS One. 2014;9(2):e88274
• ID
  MGI:5644450

Genes

Gene	Assay Type
Pcho3	visible phenotype

Notes

• Experiment
  Linkage analysis was performed on 309 (172 males; 137 females) (129S6/SvEvTac-Apoe^tm4Mae x D2.129P2(B6)-Apoe^tm1Unc/J)F2 intercross mice using 170 SNP markers to identify QTL associated with total plasma cholesterol level.
  
  QTL Pcho3 maps to 71-83 Mb (43-50 cM) on Chromosome 11 with a peak LOD score of 6.4 at 83 Mb (50 cM) in linkage with total plasma cholesterol level. 129S6/SvEvTac-Apoe alleles confer increased total plasma cholesterol level.