Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  3
• Reference
  J:170709 Di Curzio DL, et al., The genetic basis of adrenal gland weight and structure in BXD recombinant inbred mice. Mamm Genome. 2011 Apr;22(3-4):209-34
• ID
  MGI:5698432

Genes

Gene	Assay Type
Fawq1	visible phenotype
Pitx2
Hnl

Notes

• Experiment
  Linkage analysis was performed on 64 BXD RI strains (n = 528) to identify QTL associated with adrenal weight in females.
  
  QTL Fawq1 maps to 127 - 129.5 Mb on Chromosome 3 with a peak LOD score of 4.267 in linkage with female adrenal weight. DBA/2J alleles increase adrenal weight at the Fawq1 locus. The protein coding genes Pitx2 and Hnl have been identified as potential Fawq1 candidate genes.
  
  Suggestive QTL for female adrenal weight were mapped to chromosomes 1, 3, 10, and 14.