Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  10
• Reference
  J:163117 Noben-Trauth K, et al., Phenotype and genetics of progressive sensorineural hearing loss (Snhl1) in the LXS set of recombinant inbred strains of mice. PLoS One. 2010;5(7):e11459
• ID
  MGI:5776378

Genes

Gene	Assay Type
Snhl1	visible phenotype

Notes

• Experiment
  Linkage analysis was performed on a mapping population of 252 male and female (ILS x ISS) RI mice (LXS, 63 strains, 4 mice/strain) to identify one genomic locus related to sensorineural hearing loss. Mice were genotyped at 11,000 SNP markers.
  
  QTL Snhl1 maps to 54.0 - 60.0 Mb on Chromosome 10 with a peak LOD score of 15.8. ISS-derived alleles are reported to be associated with the sensorineural hearing loss phenotype. Protein-coding gene Cdh23 is suggested as the most likely candidate gene.