Mapping Data Summary

• Symbol: Npc1
• Name: NPC intracellular cholesterol transporter 1
• ID: MGI:1097712
• Chromosome: 18

10 mapping experiments

Experiment Type	Details	Chromosome	Reference
CROSS	Cross Type: Backcross	18	J:39614 Erickson RP, et al., High-resolution mapping of the spm (Niemann-Pick Type C) locus on mouse chromosome 18. Mamm Genome. 1997 May;8(5):355-6
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	18	J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
CROSS	Cross Type: Backcross	18	J:3259 Sakai Y, et al., A molecular genetic linkage map of mouse chromosome 18, including spm, Grl-1, Fim-2/c-fms, and Mbp. Biochem Genet. 1991 Feb;29(1-2):103-13
TEXT-Genetic Cross		18	J:87349 JAX Neuroscience Mutagenesis Facility, Heritable mouse mutants from JAX NMF ENU Mutagenesis Program. MGI Direct Data Submission. 2004-7;
TEXT-Genetic Cross		18	J:41469 Loftus SK, et al., Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene [see comments]. Science. 1997 Jul 11;277(5323):232-5
TEXT-Physical Mapping		18	J:64316 Hsu SJ, et al., Fine linkage and physical mapping suggests cross-over suppression with a retroposon insertion at the npc1 mutation. Mamm Genome. 2000 Sep;11(9):774-8
TEXT-Physical Mapping		18	J:41469 Loftus SK, et al., Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene [see comments]. Science. 1997 Jul 11;277(5323):232-5
TEXT-Physical Mapping		18	J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
TEXT-QTL		18	J:105074 Darakhshan F, et al., Evidence for complex multigenic inheritance of radiation AML susceptibility in mice revealed using a surrogate phenotypic assay. Carcinogenesis. 2006 Feb;27(2):311-8
TEXT-Radiation Hybrid		18	J:68900 The Jackson Laboratory Mouse Radiation Hybrid Database, Mouse T31 Radiation Hybrid Data Load. Database Release. 2004;