Mapping Data Summary

• Symbol: Apc
• Name: APC, WNT signaling pathway regulator
• ID: MGI:88039
• Chromosome: 18

20 mapping experiments

Experiment Type	Details	Chromosome	Reference
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	18	J:18927 Buxton RS, et al., Mouse desmocollin (Dsc3) and desmoglein (Dsg1) genes are closely linked in the proximal region of chromosome 18. Genomics. 1994 Jun;21(3):510-6
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	18	J:15105 Gorbea CM, et al., Cloning, expression, and chromosomal localization of the mouse meprin beta subunit. J Biol Chem. 1993 Oct 5;268(28):21035-43
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	18	J:35477 Hasson T, et al., Mapping of unconventional myosins in mouse and human. Genomics. 1996 Sep 15;36(3):431-9
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	18	J:22181 Ishikawa H, et al., cDNA cloning and chromosomal assignment of the mouse gene for desmoglein 3 (Dsg3), the pemphigus vulgaris antigen. Mamm Genome. 1994 Dec;5(12):803-4
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	18	J:1701 Justice MJ, et al., A molecular genetic linkage map of mouse chromosome 18 reveals extensive linkage conservation with human chromosomes 5 and 18. Genomics. 1992 Aug;13(4):1281-8
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	18	J:35909 Lock LF, et al., The Cdc25 genes map to mouse chromosomes 2, 9, and 18. Mamm Genome. 1996 Oct;7(10):771-2
CROSS	Cross Type: Backcross	18	J:3803 Luongo C, et al., Mapping of multiple intestinal neoplasia (Min) to proximal chromosome 18 of the mouse. Genomics. 1993 Jan;15(1):3-8
CROSS	Cross Type: Backcross	18	J:3803 Luongo C, et al., Mapping of multiple intestinal neoplasia (Min) to proximal chromosome 18 of the mouse. Genomics. 1993 Jan;15(1):3-8
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	18	J:53316 Mao NC, et al., The murine Bin1 gene functions early in myogenesis and defines a new region of synteny between mouse chromosome 18 and human chromosome 2. Genomics. 1999 Feb 15;56(1):51-8
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	18	J:27407 Pathak BG, et al., Mouse chromosomal location of three EGF receptor ligands: amphiregulin (Areg), betacellulin (Btc), and heparin-binding EGF (Hegfl). Genomics. 1995 Jul 1;28(1):116-8
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	18	J:64348 Sims JE, et al., Molecular cloning and biological characterization of a novel murine lymphoid growth factor. J Exp Med. 2000 Sep 4;192(5):671-80
TEXT		18	J:21369 Luongo C, et al., Loss of Apc+ in intestinal adenomas from Min mice. Cancer Res. 1994 Nov 15;54(22):5947-52
TEXT		18	J:34941 Pataer A, et al., Two dominant host resistance genes to pre-B lymphoma in wild-derived inbred mouse strain MSM/Ms. Cancer Res. 1996 Aug 15;56(16):3716-20
TEXT		18	J:73854 Silverman KA, et al., Identification of the modifier of Min 2 (Mom2) locus, a new mutation that influences Apc-induced intestinal neoplasia. Genome Res. 2002 Jan;12(1):88-97
TEXT		18	J:39174 Smits R, et al., Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis. Carcinogenesis. 1997 Feb;18(2):321-7
TEXT		18	J:39174 Smits R, et al., Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis. Carcinogenesis. 1997 Feb;18(2):321-7
TEXT-Physical Mapping		18	J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
TEXT-QTL		18	J:72978 Farmer MA, et al., A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13820-5
TEXT-QTL		18	J:96833 Haines J, et al., Genetic basis of variation in adenoma multiplicity in ApcMin/+ Mom1S mice. Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2868-73
TEXT-Radiation Hybrid		18	J:68900 The Jackson Laboratory Mouse Radiation Hybrid Database, Mouse T31 Radiation Hybrid Data Load. Database Release. 2004;