Mapping Data Summary

• Symbol: Apoa2
• Name: apolipoprotein A-II
• ID: MGI:88050
• Chromosome: 1

77 mapping experiments

Experiment Type	Details	Chromosome	Reference
CROSS	Cross Type: Backcross Mapping Panel: Seldin	1	J:9902 Baniyash M, et al., The isolation and characterization of the murine T cell antigen receptor zeta chain gene. J Biol Chem. 1989 Aug 5;264(22):13252-7
CROSS	Cross Type: Backcross	1	J:11049 Dowbenko DJ, et al., Characterization of the murine homing receptor gene reveals correspondence between protein domains and coding exons. Genomics. 1991 Feb;9(2):270-7
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	1	J:78956 Johnstone CN, et al., Analysis of the regulation of the A33 antigen gene reveals intestine-specific mechanisms of gene expression. J Biol Chem. 2002 Sep 13;277(37):34531-9
CROSS	Cross Type: Backcross Mapping Panel: Seldin	1	J:26856 Kingsmore SF, et al., Physical and genetic linkage of the genes encoding Ly-9 and CD48 on mouse and human chromosomes 1. Immunogenetics. 1995;42(1):59-62
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	1	J:18647 Ko MS, et al., Genetic mapping of 40 cDNA clones on the mouse genome by PCR. Mamm Genome. 1994 Jun;5(6):349-55
CROSS	Cross Type: Backcross Mapping Panel: UCLA (BSB)	1	J:20152 LeBoeuf RC, et al., Mapping of the gene for high-density lipoprotein binding protein (Hdlbp) to proximal mouse chromosome 1. Genomics. 1994 Sep 1;23(1):296-8
CROSS	Cross Type: Backcross Mapping Panel: EUCIB (BSB)	1	J:42073 Meiner VL, et al., Adrenocortical lipid depletion gene (ald) in AKR mice is associated with an acyl-CoA:cholesterol acyltransferase (ACAT) mutation. J Biol Chem. 1998 Jan 9;273(2):1064-9
CROSS	Cross Type: Backcross Mapping Panel: Seldin	1	J:10139 Moseley WS, et al., Definition of mouse chromosome 1 and 3 gene linkage groups that are conserved on human chromosome 1: evidence that a conserved linkage group spans the centromere of human chromosome 1. Genomics. 1989 Nov;5(4):899-905
CROSS	Cross Type: Backcross	1	J:29379 Mullick A, et al., Nhlh1, a basic helix-loop-helix transcription factor, is very tightly linked to the mouse looptail (Lp) mutation. Mamm Genome. 1995 Oct;6(10):700-4
CROSS	Cross Type: Backcross	1	J:29379 Mullick A, et al., Nhlh1, a basic helix-loop-helix transcription factor, is very tightly linked to the mouse looptail (Lp) mutation. Mamm Genome. 1995 Oct;6(10):700-4
CROSS	Cross Type: Backcross	1	J:25243 Mullick A, et al., High-resolution linkage map in the vicinity of the Lp locus. Genomics. 1995 Apr 10;26(3):479-88
CROSS	Cross Type: Backcross	1	J:25243 Mullick A, et al., High-resolution linkage map in the vicinity of the Lp locus. Genomics. 1995 Apr 10;26(3):479-88
CROSS	Cross Type: Backcross Mapping Panel: Seldin	1	J:9942 Opdenakker G, et al., Interferons as gene activators: a cluster of six interferon-activatable genes is linked to the erythroid alpha-spectrin locus on murine chromosome 1. Virology. 1989 Aug;171(2):568-78
CROSS	Cross Type: Backcross	1	J:9135 Paigen B, et al., Genetic analysis of murine strains C57BL/6J and C3H/HeJ to confirm the map position of Ath-1, a gene determining atherosclerosis susceptibility. Biochem Genet. 1987 Aug;25(7-8):501-11
CROSS	Cross Type: Intercross	1	J:9185 Paigen B, et al., Genetic analysis of strains C57BL/6J and BALB/cJ for Ath-1, a gene determining atherosclerosis susceptibility in mice. Biochem Genet. 1987 Dec;25(11-12):881-92
CROSS	Cross Type: Backcross	1	J:9185 Paigen B, et al., Genetic analysis of strains C57BL/6J and BALB/cJ for Ath-1, a gene determining atherosclerosis susceptibility in mice. Biochem Genet. 1987 Dec;25(11-12):881-92
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	1	J:18140 Rowe LB, et al., Maps from two interspecific backcross DNA panels available as a community genetic mapping resource [published erratum appears in Mamm Genome 1994 Jul;5(7):463]. Mamm Genome. 1994 May;5(5):253-74
CROSS	Cross Type: Backcross Mapping Panel: Seldin	1	J:56486 Seldin MF, et al., Chromosomal mapping of Adam9, Adam15 and Adam21. Matrix Biol. 2000 May;19(2):185-7
CROSS	Cross Type: Backcross Mapping Panel: Seldin	1	J:9067 Seldin MF, et al., Genetic analysis of autoimmune gld mice. I. Identification of a restriction fragment length polymorphism closely linked to the gld mutation within a conserved linkage group. J Exp Med. 1988 Feb 1;167(2):688-93
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	1	J:55251 Tang T, et al., Molecular cloning and characterization of a mouse gene with homology to the Duffy-antigen receptor for chemokines. DNA Seq. 1998;9(3):129-43
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	1	J:50058 Tullis K, et al., Mapping of the mouse Constitutive Androstane Receptor gene (Care2) to Chromosome 1. MGI Direct Data Submission. 1998;
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	1	J:29712 Uelmen PJ, et al., Tissue-specific expression and cholesterol regulation of acylcoenzyme A:cholesterol acyltransferase (ACAT) in mice. Molecular cloning of mouse ACAT cDNA, chromosomal localization, and regulation of ACAT in vivo and in vitro. J Biol Chem. 1995 Nov 3;270(44):26192-201
CROSS	Cross Type: Backcross Mapping Panel: UCLA (BSB)	1	J:38541 Welch CL, et al., Localization of the mouse glucocorticoid receptor-interacting protein 1 gene (Grip1) to proximal chromosome 1 by linkage analysis. Mamm Genome. 1997 Aug;8(8):620-1
CROSS	Cross Type: Backcross Mapping Panel: UCLA (BSB)	1	J:34178 Welch CL, et al., Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. J Lipid Res. 1996 Jul;37(7):1406-21
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	1	J:49057 Yamazaki K, et al., Cloning of 5'-flanking region and a polymorphic CTT trinucleotide repeat within 5'-untranslated region of mouse R-type calcium channel alpha1-subunit (Cchra1) gene, and its genetic mapping. Gene. 1998 Jul 3;214(1-2):199-204
RI	RI/RC Set: CXB	1	J:1025 Hwa JJ, et al., Genetic and dietary interactions in the regulation of HMG-CoA reductase gene expression. J Lipid Res. 1992 May;33(5):711-25
RI	RI/RC Set: CXB	1	J:7017 Lusis AJ, et al., Genetic control of lipid transport in mice. II. Genes controlling structure of high density lipoproteins. J Biol Chem. 1983 Apr 25;258(8):5071-8
RI	RI/RC Set: BXH	1	J:7017 Lusis AJ, et al., Genetic control of lipid transport in mice. II. Genes controlling structure of high density lipoproteins. J Biol Chem. 1983 Apr 25;258(8):5071-8
RI	RI/RC Set: BXH	1	J:4733 Mehrabian M, et al., Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice [published erratum appears in Arterioscler Thromb 1993 Mar;13(3):466]. Arterioscler Thromb. 1993 Jan;13(1):1-10
RI	RI/RC Set: NXSM	1	J:4733 Mehrabian M, et al., Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice [published erratum appears in Arterioscler Thromb 1993 Mar;13(3):466]. Arterioscler Thromb. 1993 Jan;13(1):1-10
RI	RI/RC Set: BXH	1	J:8069 Mortensen RF, et al., Mouse serum amyloid P-component (SAP) levels controlled by a locus on chromosome 1. Immunogenetics. 1985;22(4):367-75
RI	RI/RC Set: BXD	1	J:9942 Opdenakker G, et al., Interferons as gene activators: a cluster of six interferon-activatable genes is linked to the erythroid alpha-spectrin locus on murine chromosome 1. Virology. 1989 Aug;171(2):568-78
RI	RI/RC Set: CXB	1	J:9942 Opdenakker G, et al., Interferons as gene activators: a cluster of six interferon-activatable genes is linked to the erythroid alpha-spectrin locus on murine chromosome 1. Virology. 1989 Aug;171(2):568-78
RI	RI/RC Set: BXH	1	J:9135 Paigen B, et al., Genetic analysis of murine strains C57BL/6J and C3H/HeJ to confirm the map position of Ath-1, a gene determining atherosclerosis susceptibility. Biochem Genet. 1987 Aug;25(7-8):501-11
RI	RI/RC Set: BXH	1	J:8735 Paigen B, et al., Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice. Proc Natl Acad Sci U S A. 1987 Jun;84(11):3763-7
RI	RI/RC Set: CXB	1	J:8735 Paigen B, et al., Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice. Proc Natl Acad Sci U S A. 1987 Jun;84(11):3763-7
RI	RI/RC Set: AXB	1	J:9832 Paigen B, et al., Ath-2, a second gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice. Genetics. 1989 May;122(1):163-8
RI	RI/RC Set: BXA	1	J:9832 Paigen B, et al., Ath-2, a second gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice. Genetics. 1989 May;122(1):163-8
RI	RI/RC Set: BXH	1	J:8744 Seldin MF, et al., Mapping of alpha-spectrin on distal mouse chromosome 1. Cytogenet Cell Genet. 1987;45(1):52-4
RI	RI/RC Set: AKXD	1	J:9230 Seldin MF, et al., Establishment of a molecular genetic map of distal mouse chromosome 1: further definition of a conserved linkage group syntenic with human chromosome 1q. Genomics. 1988 Jan;2(1):48-56
RI	RI/RC Set: AKXL	1	J:9230 Seldin MF, et al., Establishment of a molecular genetic map of distal mouse chromosome 1: further definition of a conserved linkage group syntenic with human chromosome 1q. Genomics. 1988 Jan;2(1):48-56
RI	RI/RC Set: BXD	1	J:9230 Seldin MF, et al., Establishment of a molecular genetic map of distal mouse chromosome 1: further definition of a conserved linkage group syntenic with human chromosome 1q. Genomics. 1988 Jan;2(1):48-56
RI	RI/RC Set: AXB	1	J:9230 Seldin MF, et al., Establishment of a molecular genetic map of distal mouse chromosome 1: further definition of a conserved linkage group syntenic with human chromosome 1q. Genomics. 1988 Jan;2(1):48-56
RI	RI/RC Set: BXH	1	J:9230 Seldin MF, et al., Establishment of a molecular genetic map of distal mouse chromosome 1: further definition of a conserved linkage group syntenic with human chromosome 1q. Genomics. 1988 Jan;2(1):48-56
RI	RI/RC Set: BXA	1	J:9230 Seldin MF, et al., Establishment of a molecular genetic map of distal mouse chromosome 1: further definition of a conserved linkage group syntenic with human chromosome 1q. Genomics. 1988 Jan;2(1):48-56
RI	RI/RC Set: BXD	1	J:10552 Wong YW, et al., Structure, expression, and genetic linkage of the mouse BCM1 (OX45 or Blast-1) antigen. Evidence for genetic duplication giving rise to the BCM1 region on mouse chromosome 1 and the CD2/LFA3 region on mouse chromosome 3. J Exp Med. 1990 Jun 1;171(6):2115-30
TEXT		1	J:4733 Mehrabian M, et al., Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice [published erratum appears in Arterioscler Thromb 1993 Mar;13(3):466]. Arterioscler Thromb. 1993 Jan;13(1):1-10
TEXT		1	J:8744 Seldin MF, et al., Mapping of alpha-spectrin on distal mouse chromosome 1. Cytogenet Cell Genet. 1987;45(1):52-4
TEXT		1	J:52853 Underhill DA, et al., Physical delineation of a 700-kb region overlapping the Looptail mutation on mouse chromosome 1. Genomics. 1999 Jan 15;55(2):185-93
TEXT		1	J:39861 Wang J, et al., Regulation of the metabolism of plasma lipoproteins by apolipoprotein A-II. Biochim Biophys Acta. 1997 Apr 21;1345(3):248-58
TEXT		1	J:39861 Wang J, et al., Regulation of the metabolism of plasma lipoproteins by apolipoprotein A-II. Biochim Biophys Acta. 1997 Apr 21;1345(3):248-58
TEXT-Genetic Cross		1	J:57247 Hurskainen TL, et al., ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family. J Biol Chem. 1999 Sep 3;274(36):25555-63
TEXT-Genetic Cross		1	J:29379 Mullick A, et al., Nhlh1, a basic helix-loop-helix transcription factor, is very tightly linked to the mouse looptail (Lp) mutation. Mamm Genome. 1995 Oct;6(10):700-4
TEXT-Genetic Cross		1	J:29379 Mullick A, et al., Nhlh1, a basic helix-loop-helix transcription factor, is very tightly linked to the mouse looptail (Lp) mutation. Mamm Genome. 1995 Oct;6(10):700-4
TEXT-Genetic Cross		1	J:9342 Seldin MF, et al., A molecular genetic approach to gld autoimmune disease. Curr Top Microbiol Immunol. 1988;137:227-32
TEXT-Genetic Cross		1	J:15567 Warden CH, et al., Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse. Genomics. 1993 Nov;18(2):295-307
TEXT-Physical Mapping		1	J:52606 Eddleston J, et al., Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp). Genomics. 1999 Mar 1;56(2):149-59
TEXT-Physical Mapping		1	J:3288 Oakey RJ, et al., Construction of a physical map on mouse and human chromosome 1: comparison of 13 Mb of mouse and 11 Mb of human DNA. Hum Mol Genet. 1992 Nov;1(8):613-20
TEXT-QTL		1	J:76127 Dansky HM, et al., A phenotype-sensitizing apoe-deficient genetic background reveals novel atherosclerosis predisposition Loci in the mouse. Genetics. 2002 Apr;160(4):1599-608
TEXT-QTL		1	J:88486 Ishimori N, et al., Quantitative trait loci analysis for plasma HDL-cholesterol concentrations and atherosclerosis susceptibility between inbred mouse strains C57BL/6J and 129S1/SvImJ. Arterioscler Thromb Vasc Biol. 2004 Jan;24(1):161-6
TEXT-QTL		1	J:89309 Korstanje R, et al., Influence of sex and diet on quantitative trait loci for HDL cholesterol levels in an SM/J by NZB/BlNJ intercross population. J Lipid Res. 2004 May;45(5):881-8
TEXT-QTL		1	J:89282 Lyons MA, et al., Genetic contributors to lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and RIIIS/J inbred mice. Physiol Genomics. 2004 Apr 13;17(2):114-21
TEXT-QTL		1	J:88732 Lyons MA, et al., Quantitative trait loci that determine lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and CAST/Ei inbred mice. Physiol Genomics. 2004 Mar 12;17(1):60-8
TEXT-QTL		1	J:4733 Mehrabian M, et al., Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice [published erratum appears in Arterioscler Thromb 1993 Mar;13(3):466]. Arterioscler Thromb. 1993 Jan;13(1):1-10
TEXT-QTL		1	J:32090 Muller-Sieburg CE, et al., Genetic control of the frequency of hematopoietic stem cells in mice: mapping of a candidate locus to chromosome 1. J Exp Med. 1996 Mar 1;183(3):1141-50
TEXT-QTL		1	J:29072 Purcell-Huynh DA, et al., Genetic factors in lipoprotein metabolism. Analysis of a genetic cross between inbred mouse strains NZB/BINJ and SM/J using a complete linkage map approach. J Clin Invest. 1995 Oct;96(4):1845-58
TEXT-QTL		1	J:72738 Schwarz M, et al., Genetic analysis of cholesterol accumulation in inbred mice. J Lipid Res. 2001 Nov;42(11):1812-9
TEXT-QTL		1	J:106033 Srivastava AK, et al., Identification of quantitative trait loci that regulate obesity and serum lipid levels in MRL/MpJ x SJL/J inbred mice. J Lipid Res. 2006 Jan;47(1):123-33
TEXT-QTL		1	J:108422 Su Z, et al., Genetic linkage of hyperglycemia, body weight and serum amyloid-P in an intercross between C57BL/6 and C3H apolipoprotein E-deficient mice. Hum Mol Genet. 2006 May 15;15(10):1650-8
TEXT-QTL		1	J:106521 Su Z, et al., Quantitative Trait Locus Analysis of Atherosclerosis in an Intercross Between C57BL/6 and C3H Mice Carrying the Mutant Apolipoprotein E Gene. Genetics. 2006 Mar;172(3):1799-807
TEXT-QTL		1	J:94251 Suto J, et al., Quantitative trait locus analysis of plasma cholesterol and triglyceride levels in C57BL/6J x RR F2 mice. Biochem Genet. 2004 Oct;42(9-10):347-63
TEXT-QTL		1	J:111630 Valdar W, et al., Genome-wide genetic association of complex traits in heterogeneous stock mice. Nat Genet. 2006 Aug;38(8):879-87
TEXT-QTL		1	J:127711 Wang SS, et al., Mapping, genetic isolation, and characterization of genetic loci that determine resistance to atherosclerosis in C3H mice. Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2671-6
TEXT-QTL		1	J:84430 Wang X, et al., Using advanced intercross lines for high-resolution mapping of HDL cholesterol quantitative trait loci. Genome Res. 2003 Jul;13(7):1654-64
TEXT-QTL-Candidate Genes		1	J:99477 Brown AC, et al., Searching QTL by gene expression: analysis of diabesity. BMC Genet. 2005 Mar 10;6(1):12
TEXT-QTL-Candidate Genes		1	J:133501 Stylianou IM, et al., Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification. Genetics. 2008 Mar;178(3):1795-805
TEXT-QTL-Candidate Genes		1	J:99474 Suto J, Apolipoprotein gene polymorphisms as cause of cholesterol QTLs in mice. J Vet Med Sci. 2005 Jun;67(6):583-9