Mapping Data Summary

• Symbol: App
• Name: amyloid beta precursor protein
• ID: MGI:88059
• Chromosome: 16

48 mapping experiments

Experiment Type	Details	Chromosome	Reference
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	16	J:17787 Bae SC, et al., PEBP2 alpha B/mouse AML1 consists of multiple isoforms that possess differential transactivation potentials. Mol Cell Biol. 1994 May;14(5):3242-52
CROSS	Cross Type: Backcross	16	J:9328 Cheng SV, et al., Comparative mapping of DNA markers from the familial Alzheimer disease and Down syndrome regions of human chromosome 21 to mouse chromosomes 16 and 17. Proc Natl Acad Sci U S A. 1988 Aug;85(16):6032-6
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	16	J:31897 Fan CM, et al., Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome. Mol Cell Neurosci. 1996 Jan;7(1):1-16
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	16	J:60651 Gardner HP, et al., Cloning and characterization of Hunk, a novel mammalian SNF1-related protein kinase. Genomics. 2000 Jan 1;63(1):46-59
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	16	J:26602 Habets GG, et al., The invasion-inducing TIAM1 gene maps to human chromosome band 21q22 and mouse chromosome 16. Cytogenet Cell Genet. 1995;70(1-2):48-51
CROSS	Cross Type: Backcross	16	J:11584 Irving NG, et al., Mouse chromosome-specific markers generated by PCR and their mapping through interspecific backcrosses. Genomics. 1991 Nov;11(3):679-86
CROSS	Cross Type: Backcross	16	J:11584 Irving NG, et al., Mouse chromosome-specific markers generated by PCR and their mapping through interspecific backcrosses. Genomics. 1991 Nov;11(3):679-86
CROSS	Cross Type: Backcross	16	J:11062 Irving NG, et al., The multipoint genetic mapping of mouse chromosome 16. Genomics. 1991 Feb;9(2):386-9
CROSS	Cross Type: Backcross Mapping Panel: Kozak FvC58 + FvSpr	16	J:56825 Kozak CA, et al., Identification and genetic mapping of differentially expressed genes in mice differing at the If1 interferon regulatory locus. Mamm Genome. 1999 Sep;10(9):853-7
CROSS	Cross Type: Backcross	16	J:32823 Mariano TM, et al., Genetic mapping of the gene for the mouse interferon-gamma receptor signaling subunit to the distal end of chromosome 16. Mamm Genome. 1996 Apr;7(4):321-2
CROSS	Cross Type: Backcross Mapping Panel: Kozak FvC58 + FvSpr	16	J:32823 Mariano TM, et al., Genetic mapping of the gene for the mouse interferon-gamma receptor signaling subunit to the distal end of chromosome 16. Mamm Genome. 1996 Apr;7(4):321-2
CROSS	Cross Type: Backcross	16	J:13578 Mjaatvedt AE, et al., High-resolution mapping of D16led-1, Gart, Gas-4, Cbr, Pcp-4, and Erg on distal mouse chromosome 16. Genomics. 1993 Aug;17(2):382-6
CROSS	Cross Type: Backcross	16	J:13578 Mjaatvedt AE, et al., High-resolution mapping of D16led-1, Gart, Gas-4, Cbr, Pcp-4, and Erg on distal mouse chromosome 16. Genomics. 1993 Aug;17(2):382-6
CROSS	Cross Type: Backcross	16	J:13578 Mjaatvedt AE, et al., High-resolution mapping of D16led-1, Gart, Gas-4, Cbr, Pcp-4, and Erg on distal mouse chromosome 16. Genomics. 1993 Aug;17(2):382-6
CROSS	Cross Type: Backcross	16	J:13578 Mjaatvedt AE, et al., High-resolution mapping of D16led-1, Gart, Gas-4, Cbr, Pcp-4, and Erg on distal mouse chromosome 16. Genomics. 1993 Aug;17(2):382-6
CROSS	Cross Type: Backcross Mapping Panel: Kozak FvC58 + FvSpr	16	J:26193 Mock BA, et al., CHUK, a conserved helix-loop-helix ubiquitous kinase, maps to human chromosome 10 and mouse chromosome 19. Genomics. 1995 May 20;27(2):348-51
CROSS	Cross Type: Backcross	16	J:26193 Mock BA, et al., CHUK, a conserved helix-loop-helix ubiquitous kinase, maps to human chromosome 10 and mouse chromosome 19. Genomics. 1995 May 20;27(2):348-51
CROSS	Cross Type: Backcross	16	J:22777 Reeves RH, et al., The mouse neurological mutant weaver maps within the region of chromosome 16 that is homologous to human chromosome 21. Genomics. 1989 Oct;5(3):522-6
CROSS	Cross Type: Backcross	16	J:11081 Reeves RH, et al., Sex, strain, and species differences affect recombination across an evolutionarily conserved segment of mouse chromosome 16. Genomics. 1990 Sep;8(1):141-8
CROSS	Cross Type: Backcross	16	J:11081 Reeves RH, et al., Sex, strain, and species differences affect recombination across an evolutionarily conserved segment of mouse chromosome 16. Genomics. 1990 Sep;8(1):141-8
CROSS	Cross Type: Backcross	16	J:11081 Reeves RH, et al., Sex, strain, and species differences affect recombination across an evolutionarily conserved segment of mouse chromosome 16. Genomics. 1990 Sep;8(1):141-8
CROSS	Cross Type: Backcross	16	J:11081 Reeves RH, et al., Sex, strain, and species differences affect recombination across an evolutionarily conserved segment of mouse chromosome 16. Genomics. 1990 Sep;8(1):141-8
CROSS	Cross Type: Backcross	16	J:11081 Reeves RH, et al., Sex, strain, and species differences affect recombination across an evolutionarily conserved segment of mouse chromosome 16. Genomics. 1990 Sep;8(1):141-8
CROSS	Cross Type: Backcross	16	J:11081 Reeves RH, et al., Sex, strain, and species differences affect recombination across an evolutionarily conserved segment of mouse chromosome 16. Genomics. 1990 Sep;8(1):141-8
CROSS	Cross Type: Backcross	16	J:4467 Reeves RH, et al., Genetic linkage in the mouse of genes involved in Down syndrome and Alzheimer's disease in man. Brain Res. 1987 Sep;388(3):215-21
CROSS	Cross Type: Backcross Mapping Panel: Reeves (Chr 16)	16	J:42076 Reeves RH, et al., High-resolution recombinational map of mouse Chromosome 16. Genomics. 1997 Jul 15;43(2):202-8
CROSS	Cross Type: Backcross	16	J:18830 Roffler-Tarlov S, et al., The chromosomal location of the murine mutation weaver. Neurodegeneration. 1994;3(1):61-72
CROSS	Cross Type: Backcross	16	J:18830 Roffler-Tarlov S, et al., The chromosomal location of the murine mutation weaver. Neurodegeneration. 1994;3(1):61-72
HYBRID		16	J:8704 Lovett M, et al., The mouse homolog of the human amyloid beta protein (AD-AP) gene is located on the distal end of mouse chromosome 16: further extension of the homology between human chromosome 21 and mouse chromosome 16. Biochem Biophys Res Commun. 1987 Apr 29;144(2):1069-75
HYBRID		16	J:4467 Reeves RH, et al., Genetic linkage in the mouse of genes involved in Down syndrome and Alzheimer's disease in man. Brain Res. 1987 Sep;388(3):215-21
RI	RI/RC Set: BXD	16	J:9328 Cheng SV, et al., Comparative mapping of DNA markers from the familial Alzheimer disease and Down syndrome regions of human chromosome 21 to mouse chromosomes 16 and 17. Proc Natl Acad Sci U S A. 1988 Aug;85(16):6032-6
RI	RI/RC Set: AKXD	16	J:9328 Cheng SV, et al., Comparative mapping of DNA markers from the familial Alzheimer disease and Down syndrome regions of human chromosome 21 to mouse chromosomes 16 and 17. Proc Natl Acad Sci U S A. 1988 Aug;85(16):6032-6
RI	RI/RC Set: BXH	16	J:9328 Cheng SV, et al., Comparative mapping of DNA markers from the familial Alzheimer disease and Down syndrome regions of human chromosome 21 to mouse chromosomes 16 and 17. Proc Natl Acad Sci U S A. 1988 Aug;85(16):6032-6
RI	RI/RC Set: BXD	16	J:19614 de la Brousse FC, et al., Molecular and genetic characterization of GABP beta. Genes Dev. 1994 Aug 1;8(15):1853-65
RI	RI/RC Set: AKXD	16	J:19614 de la Brousse FC, et al., Molecular and genetic characterization of GABP beta. Genes Dev. 1994 Aug 1;8(15):1853-65
RI	RI/RC Set: Not Specified	16	J:28086 Taylor BA, et al., Typing recombinant inbred mouse strains for microsatellite markers on chromosomes 10, 16, 18, 19, and X. Mamm Genome. 1995 Aug;6(8):493-8
TEXT-Cytogenetic Localization		16	J:30229 Davisson MT, et al., Segmental trisomy as a mouse model for Down syndrome. Prog Clin Biol Res. 1993;384:117-33
TEXT-Cytogenetic Localization		16	J:29232 Reeves RH, et al., A mouse model for Down syndrome exhibits learning and behaviour deficits [see comments]. Nat Genet. 1995 Oct;11(2):177-84
TEXT-Cytogenetic Localization		16	J:12385 Reeves RH, et al., Genetic and cytologic localization of genes related to Down syndrome and Alzheimer's disease in the mouse. Cytogenet Cell Genet. 1987;46:681 (Abstr.)
TEXT-Cytogenetic Localization		16	J:4467 Reeves RH, et al., Genetic linkage in the mouse of genes involved in Down syndrome and Alzheimer's disease in man. Brain Res. 1987 Sep;388(3):215-21
TEXT-Genetic Cross		16	J:4377 Gregor P, et al., Chromosomal localization of glutamate receptor genes: relationship to familial amyotrophic lateral sclerosis and other neurological disorders of mice and humans. Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):3053-7
TEXT-Genetic Cross		16	J:2353 Irving NG, et al., A mouse chromosome 16 inter-repeat PCR product from C57BL/10 and Mus spretus forms a heteroduplex in interspecific backcross progeny. Mouse Genome. 1991;89(4):854-856
TEXT-Genetic Cross		16	J:12908 Irving NG, et al., The positions of 12 simple sequence repeat markers relative to reference loci on mouse chromosome 16. Mamm Genome. 1993;4(7):364-7
TEXT-Genetic Cross		16	J:12385 Reeves RH, et al., Genetic and cytologic localization of genes related to Down syndrome and Alzheimer's disease in the mouse. Cytogenet Cell Genet. 1987;46:681 (Abstr.)
TEXT-Physical Mapping		16	J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
TEXT-QTL		16	J:81203 Brich J, et al., Genetic modulation of tau phosphorylation in the mouse. J Neurosci. 2003 Jan 1;23(1):187-92
TEXT-QTL		16	J:84430 Wang X, et al., Using advanced intercross lines for high-resolution mapping of HDL cholesterol quantitative trait loci. Genome Res. 2003 Jul;13(7):1654-64
TEXT-Radiation Hybrid		16	J:68900 The Jackson Laboratory Mouse Radiation Hybrid Database, Mouse T31 Radiation Hybrid Data Load. Database Release. 2004;