Mapping Data Summary

• Symbol: Ctla4
• Name: cytotoxic T-lymphocyte-associated protein 4
• ID: MGI:88556
• Chromosome: 1

47 mapping experiments

Experiment Type	Details	Chromosome	Reference
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	1	J:15133 Avraham KB, et al., Murine chromosomal location of four class III POU transcription factors. Genomics. 1993 Oct;18(1):131-3
CROSS	Cross Type: Backcross Mapping Panel: Seldin	1	J:10189 Barnum SR, et al., Molecular analysis of the murine C4b-binding protein gene. Chromosome assignment and partial gene organization. Biochemistry. 1989 Oct 17;28(21):8312-7
CROSS	Cross Type: Backcross	1	J:1675 Cole TJ, et al., The mouse CREB (cAMP responsive element binding protein) gene: structure, promoter analysis, and chromosomal localization. Genomics. 1992 Aug;13(4):974-82
CROSS	Cross Type: Backcross Mapping Panel: Seldin	1	J:2945 Colombo MP, et al., Localization of growth arrest-specific genes on mouse chromosomes 1, 7, 8, 11, 13, and 16. Mamm Genome. 1992;2(2):130-4
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	1	J:3778 Copeland NG, et al., Chromosomal localization of mouse bullous pemphigoid antigens. BPAG1 and BPAG2: identification of a new region of homology between mouse and human chromosomes. Genomics. 1993 Jan;15(1):180-1
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	1	J:28833 Copeland NG, et al., Distribution of the mammalian Stat gene family in mouse chromosomes. Genomics. 1995 Sep 1;29(1):225-8
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	1	J:11044 Copeland NG, et al., Chromosomal location of murine and human IL-1 receptor genes. Genomics. 1991 Jan;9(1):44-50
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	1	J:62376 Friedman RA, et al., A transgenic insertional inner ear mutation on mouse chromosome 1. Laryngoscope. 2000 Apr;110(4):489-96
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	1	J:35477 Hasson T, et al., Mapping of unconventional myosins in mouse and human. Genomics. 1996 Sep 15;36(3):431-9
CROSS	Cross Type: Backcross Mapping Panel: Seldin	1	J:11002 Howard TA, et al., Cd28 and Ctla-4, two related members of the Ig supergene family, are tightly linked on proximal mouse chromosome 1. Immunogenetics. 1991;33(1):74-6
CROSS	Cross Type: Backcross Mapping Panel: Seldin	1	J:52605 Ishikawa T, et al., Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis. Development. 2001 Jan;128(1):25-33
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	1	J:18647 Ko MS, et al., Genetic mapping of 40 cDNA clones on the mouse genome by PCR. Mamm Genome. 1994 Jun;5(6):349-55
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	1	J:18935 Kou K, et al., Identification of two clusters of mouse insulin-like growth factor binding protein genes on chromosomes 1 and 11. Genomics. 1994 Jun;21(3):653-5
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	1	J:17634 Kou K, et al., Organization, expression, and chromosomal location of the mouse insulin-like growth factor binding protein 5 gene. Genomics. 1994 Apr;20(3):412-8
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	1	J:51779 Levy N, et al., Physical and genetic linkage of glutaminase (Gls), signal transducer and activator of transcription 1 (Stat1), and xeroderma pigmentosum complementation group G (Xpg) on mouse proximal chromosome 1. Genomics. 1998 Dec 1;54(2):355-6
CROSS	Cross Type: Backcross Mapping Panel: Seldin	1	J:10042 Mock B, et al., A glutaminase (gis) gene maps to mouse chromosome 1, rat chromosome 9, and human chromosome 2 [published erratum appears in Genomics 1989 Nov;5(4):957]. Genomics. 1989 Aug;5(2):291-7
CROSS	Cross Type: Backcross	1	J:20796 Moore KJ, et al., The murine dilute suppressor gene encodes a cell autonomous suppressor. Genetics. 1994 Oct;138(2):491-7
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	1	J:29923 Okabe I, et al., Identification and chromosomal mapping of the mouse inositol polyphosphate 1-phosphatase gene. Genomics. 1995 Nov 20;30(2):358-60
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	1	J:31188 Pathak BG, et al., Mouse chromosomal location of four Na/H exchanger isoform genes. Genomics. 1996 Jan 15;31(2):261-3
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	1	J:18140 Rowe LB, et al., Maps from two interspecific backcross DNA panels available as a community genetic mapping resource [published erratum appears in Mamm Genome 1994 Jul;5(7):463]. Mamm Genome. 1994 May;5(5):253-74
CROSS	Cross Type: Backcross	1	J:11397 Tominaga S, et al., Molecular cloning of the murine ST2 gene. Characterization and chromosomal mapping. Biochim Biophys Acta. 1991 Aug 27;1090(1):1-8
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	1	J:49459 Varfolomeev EE, et al., Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity. 1998 Aug;9(2):267-76
CROSS	Cross Type: Backcross	1	J:11577 Walther C, et al., Pax: a murine multigene family of paired box-containing genes. Genomics. 1991 Oct;11(2):424-34
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	1	J:37068 Wang Y, et al., A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled. J Biol Chem. 1996 Feb 23;271(8):4468-76
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	1	J:18883 Yamamoto K, et al., Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation. Mol Cell Biol. 1994 Jul;14(7):4342-9
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	1	J:43498 Yang Z, et al., Identification, partial characterization, and genetic mapping of kinesin-like protein genes in mouse. Genomics. 1997 Oct 1;45(1):123-31
IN SITU	Band: C	1	J:8775 Brunet JF, et al., A new member of the immunoglobulin superfamily--CTLA-4. Nature. 1987 Jul 16-22;328(6127):267-70
IN SITU	Band: C	1	J:12348 Mattei MG, et al., In situ mapping of four cytotoxic T-lymphocyte associated proteins (CTLA) to the mouse genome. Cytogenet Cell Genet. 1987;46:657-658 (Abstr.)
TEXT		1	J:72900 Lamhamedi-Cherradi SE, et al., Further Mapping of the Idd5.1 Locus for Autoimmune Diabetes in NOD Mice. Diabetes. 2001 Dec;50(12):2874-8
TEXT-Congenic		1	J:88667 Hill NJ, et al., NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans. Diabetes. 2000 Oct;49(10):1744-7
TEXT-Congenic		1	J:72900 Lamhamedi-Cherradi SE, et al., Further Mapping of the Idd5.1 Locus for Autoimmune Diabetes in NOD Mice. Diabetes. 2001 Dec;50(12):2874-8
TEXT-Congenic		1	J:90924 Wicker LS, et al., Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse. J Immunol. 2004 Jul 1;173(1):164-73
TEXT-Genetic Cross		1	J:52605 Ishikawa T, et al., Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis. Development. 2001 Jan;128(1):25-33
TEXT-Genetic Cross		1	J:1077 Le Roy H, et al., A set of anonymous DNA clones as markers for mouse gene mapping. Mamm Genome. 1992;3(4):244-6
TEXT-Genetic Cross		1	J:24197 McCarthy L, et al., Efficient high-resolution genetic mapping of mouse interspersed repetitive sequence PCR products, toward integrated genetic and physical mapping of the mouse genome. Proc Natl Acad Sci U S A. 1995 Jun 6;92(12):5302-6
TEXT-Genetic Cross		1	J:10988 Olson E, et al., Myogenin is in an evolutionarily conserved linkage group on human chromosome 1q31-q41 and unlinked to other mapped muscle regulatory factor genes. Genomics. 1990 Nov;8(3):427-34
TEXT-QTL		1	J:110034 Behnke JM, et al., High resolution mapping of chromosomal regions controlling resistance to gastrointestinal nematode infections in an advanced intercross line of mice. Mamm Genome. 2006 Jun;17(6):584-97
TEXT-QTL		1	J:68151 Bergman ML, et al., CTLA-4-/- Mice Display T Cell-apoptosis Resistance Resembling that Ascribed to Autoimmune-prone Non-obese Diabetic (NOD) Mice. J Autoimmun. 2001 Mar;16(2):105-13
TEXT-QTL		1	J:82689 Butterfield RJ, et al., Sex-Specific Quantitative Trait Loci Govern Susceptibility to Theiler's Murine Encephalomyelitis Virus-Induced Demyelination. Genetics. 2003 Mar;163(3):1041-6
TEXT-QTL		1	J:129916 Cha S, et al., IDD3 and IDD5 alleles from nod mice mediate Sjogren's syndrome-like autoimmunity. Adv Exp Med Biol. 2002;506(Pt B):1035-9
TEXT-QTL		1	J:72978 Farmer MA, et al., A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13820-5
TEXT-QTL		1	J:60445 Haywood ME, et al., Identification of intervals on chromosomes 1, 3, and 13 linked to the development of lupus in BXSB mice. Arthritis Rheum. 2000 Feb;43(2):349-55
TEXT-QTL		1	J:76931 Hsu HC, et al., Age-related change in thymic T-cell development is associated with genetic loci on mouse chromosomes 1, 3, and 11. Mech Ageing Dev. 2002 Apr;123(8):1145-58
TEXT-QTL		1	J:99793 Mazon Pelaez I, et al., Identification of quantitative trait loci controlling cortical motor evoked potentials in experimental autoimmune encephalomyelitis: correlation with incidence, onset and severity of disease. Hum Mol Genet. 2005 Jul 15;14(14):1977-89
TEXT-QTL-Candidate Genes		1	J:71276 Brayer J, et al., Alleles from chromosomes 1 and 3 of NOD mice combine to influence Sjogren's syndrome-like autoimmune exocrinopathy. J Rheumatol. 2000 Aug;27(8):1896-904
TEXT-QTL-Candidate Genes		1	J:289996 Noyes H, et al., Evidence for genes controlling resistance to Heligmosomoides bakeri on mouse chromosome 1. Parasitology. 2015 Apr;142(4):566-75
TEXT-QTL-Candidate Genes		1	J:83656 Ueda H, et al., Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature. 2003 May 29;423(6939):506-11