Mapping Data Summary

• Symbol: Hc
• Name: hemolytic complement
• ID: MGI:96031
• Chromosome: 2

72 mapping experiments

Experiment Type	Details	Chromosome	Reference
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	2	J:1773 Askew DS, et al., His-1 and His-2: identification and chromosomal mapping of two commonly rearranged sites of viral integration in a myeloid leukemia. Oncogene. 1991 Nov;6(11):2041-7
CROSS	Cross Type: Backcross	2	J:9457 Birkenmeier CS, et al., Chromosomal location of three spectrin genes: relationship to the inherited hemolytic anemias of mouse and man. Proc Natl Acad Sci U S A. 1988 Nov;85(21):8121-5
CROSS	Cross Type: Intercross	2	J:34880 Brunialti AL, et al., The mouse mutation sarcosinemia (sar) maps to chromosome 2 in a region homologous to human 9q33-q34. Genomics. 1996 Aug 15;36(1):182-4
CROSS	Cross Type: Backcross	2	J:6769 Colombatti A, et al., Gene for a major cell surface glycoprotein of mouse macrophages and other phagocytic cells is on chromosome 2. Proc Natl Acad Sci U S A. 1982 Mar;79(6):1926-9
CROSS	Cross Type: Backcross	2	J:8488 D'Eustachio P, et al., Chromosomal location of the genes encoding complement components C5 and factor H in the mouse. J Immunol. 1986 Dec 15;137(12):3990-5
CROSS	Cross Type: Backcross	2	J:8488 D'Eustachio P, et al., Chromosomal location of the genes encoding complement components C5 and factor H in the mouse. J Immunol. 1986 Dec 15;137(12):3990-5
CROSS	Cross Type: Backcross	2	J:8488 D'Eustachio P, et al., Chromosomal location of the genes encoding complement components C5 and factor H in the mouse. J Immunol. 1986 Dec 15;137(12):3990-5
CROSS	Cross Type: Backcross	2	J:4221 Dutton ER Williamson P, et al., D2Har1 detected by clone pG3.1 maps between Acra and Il-1b on chromosome 2. Mouse Genome. 1993;91(1):121-23
CROSS	Cross Type: Backcross	2	J:8601 Hogarth PM, et al., Mapping of the mouse Ly-6, Xp-14, and Gdc-1 loci to chromosome 15. Immunogenetics. 1987;25(1):21-7
CROSS	Cross Type: Backcross	2	J:4381 Hunt CR, et al., Chromosomal localization of five murine HSP70 gene family members: Hsp70-1, Hsp70-2, Hsp70-3, Hsc70t, and Grp78. Genomics. 1993 Apr;16(1):193-8
CROSS	Cross Type: Backcross	2	J:10278 Joseph DR, et al., Characterization and expression of the complementary DNA encoding rat histidine decarboxylase [published erratum appears in Proc Natl Acad Sci U S A 1990 Sep;87(18):7346]. Proc Natl Acad Sci U S A. 1990 Jan;87(2):733-7
CROSS	Cross Type: Backcross	2	J:11100 Joziasse DH, et al., Gene for murine alpha 1----3-galactosyltransferase is located in the centromeric region of chromosome 2. Somat Cell Mol Genet. 1991 Mar;17(2):201-5
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	2	J:35593 Kasahara M, et al., Chromosomal localization of the proteasome Z subunit gene reveals an ancient chromosomal duplication involving the major histocompatibility complex. Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):9096-101
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	2	J:29856 Mbikay M, et al., Linkage mapping of the gene for the LIM-homeoprotein LIM3 (locus Lhx3) to mouse chromosome 2. Mamm Genome. 1995 Nov;6(11):818-9
CROSS	Cross Type: Backcross	2	J:44 Moen CJ, et al., Scc-1, a novel colon cancer susceptibility gene in the mouse: linkage to CD44 (Ly-24, Pgp-1) on chromosome 2. Oncogene. 1992 Mar;7(3):563-6
CROSS	Cross Type: Backcross	2	J:44 Moen CJ, et al., Scc-1, a novel colon cancer susceptibility gene in the mouse: linkage to CD44 (Ly-24, Pgp-1) on chromosome 2. Oncogene. 1992 Mar;7(3):563-6
CROSS	Cross Type: Backcross	2	J:7742 Natsuume-Sakai S, et al., Structural polymorphism of murine complement factor H controlled by a locus located between the Hc and the beta 2M locus on the second chromosome of the mouse. J Immunol. 1985 Apr;134(4):2600-6
CROSS	Cross Type: Backcross	2	J:10894 Paul R, et al., The Sfpi-1 proviral integration site of Friend erythroleukemia encodes the ets-related transcription factor Pu.1. J Virol. 1991 Jan;65(1):464-7
CROSS	Cross Type: Backcross	2	J:331 Pilz A, et al., Comparative mapping of mouse chromosome 2 and human chromosome 9q: the genes for gelsolin and dopamine beta-hydroxylase map to mouse chromosome 2. Genomics. 1992 Apr;12(4):715-9
CROSS	Cross Type: Backcross Mapping Panel: EUCIB (BSS)	2	J:38089 Pilz A, et al., High resolution genetic linkage analysis of mouse Chromosome 2 in the region of homology with human Chromosome 9. Mouse Genome. 1996;94(4):877-9
CROSS	Cross Type: Backcross	2	J:18301 Pilz A, et al., Genetic linkage analysis of the Ak1, Col5a1, Epb7.2, Fpgs, Grp78, Pbx3, and Notch1 genes in the region of mouse chromosome 2 homologous to human chromosome 9q. Genomics. 1994 May 1;21(1):104-9
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSB)	2	J:18301 Pilz A, et al., Genetic linkage analysis of the Ak1, Col5a1, Epb7.2, Fpgs, Grp78, Pbx3, and Notch1 genes in the region of mouse chromosome 2 homologous to human chromosome 9q. Genomics. 1994 May 1;21(1):104-9
CROSS	Cross Type: Backcross	2	J:22833 Pilz A, et al., Comparative mapping of 50 human chromosome 9 loci in the laboratory mouse. Genomics. 1995 Jan 1;25(1):139-49
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSB)	2	J:22833 Pilz A, et al., Comparative mapping of 50 human chromosome 9 loci in the laboratory mouse. Genomics. 1995 Jan 1;25(1):139-49
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSB)	2	J:18140 Rowe LB, et al., Maps from two interspecific backcross DNA panels available as a community genetic mapping resource [published erratum appears in Mamm Genome 1994 Jul;5(7):463]. Mamm Genome. 1994 May;5(5):253-74
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	2	J:18140 Rowe LB, et al., Maps from two interspecific backcross DNA panels available as a community genetic mapping resource [published erratum appears in Mamm Genome 1994 Jul;5(7):463]. Mamm Genome. 1994 May;5(5):253-74
CROSS	Cross Type: Backcross Mapping Panel: Kozak Skive	2	J:11405 Shapiro M, et al., Genetic mapping in the mouse of four loci related to the jun family of transcriptional activators. Somat Cell Mol Genet. 1991 Jul;17(4):341-7
CROSS	Cross Type: Backcross	2	J:11464 Siracusa LD, et al., Interspecific backcross mice show sex-specific differences in allelic inheritance. Genetics. 1991 Aug;128(4):813-21
CROSS	Cross Type: Backcross	2	J:11464 Siracusa LD, et al., Interspecific backcross mice show sex-specific differences in allelic inheritance. Genetics. 1991 Aug;128(4):813-21
CROSS	Cross Type: Backcross	2	J:11464 Siracusa LD, et al., Interspecific backcross mice show sex-specific differences in allelic inheritance. Genetics. 1991 Aug;128(4):813-21
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	2	J:11120 Siracusa LD, et al., Identification and applications of repetitive probes for gene mapping in the mouse. Genetics. 1991 Jan;127(1):169-79
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	2	J:10439 Siracusa LD, et al., A molecular genetic linkage map of mouse chromosome 2. Genomics. 1990 Mar;6(3):491-504
HYBRID		2	J:8488 D'Eustachio P, et al., Chromosomal location of the genes encoding complement components C5 and factor H in the mouse. J Immunol. 1986 Dec 15;137(12):3990-5
RI	RI/RC Set: BXD	2	J:17829 Allen KM, et al., Genetic analysis of nucleotide triphosphatase activity in the mouse brain. Genetics. 1994 May;137(1):257-65
RI	RI/RC Set: NXSM	2	J:10663 Eicher EM, et al., The NXSM recombinant inbred strains of mice: genetic profile for 58 loci including the Mtv proviral loci. Genetics. 1990 Jun;125(2):431-46
RI	RI/RC Set: NXSM	2	J:1883 Frankel WN, et al., Characterization of the endogenous nonecotropic murine leukemia viruses of NZB/B1NJ and SM/J inbred strains. Mamm Genome. 1992;2(2):110-22
RI	RI/RC Set: SWXJ	2	J:3522 Gaskins HR, et al., Chromosomal localization of the murine stress protein gene encoding glucose-regulated protein 78 (BiP). Mamm Genome. 1992;3(12):709-11
RI	RI/RC Set: SWXL	2	J:3522 Gaskins HR, et al., Chromosomal localization of the murine stress protein gene encoding glucose-regulated protein 78 (BiP). Mamm Genome. 1992;3(12):709-11
RI	RI/RC Set: AXB	2	J:7345 Gervais F, et al., Genetic control of resistance to Listeria monocytogenes: regulation of leukocyte inflammatory responses by the Hc locus. J Immunol. 1984 Apr;132(4):2078-83
RI	RI/RC Set: BXA	2	J:7345 Gervais F, et al., Genetic control of resistance to Listeria monocytogenes: regulation of leukocyte inflammatory responses by the Hc locus. J Immunol. 1984 Apr;132(4):2078-83
RI	RI/RC Set: CXS	2	J:8016 Hilgers J, et al., A series of recombinant inbred strains between the BALB/cHeA and STS/A mouse strains. Curr Top Microbiol Immunol. 1985;122:31-7
RI	RI/RC Set: SWXL	2	J:10442 Jackson MJ, et al., Assignment of the structural gene for argininosuccinate synthetase to proximal mouse chromosome 2. Genomics. 1990 Mar;6(3):545-7
RI	RI/RC Set: BXD	2	J:10442 Jackson MJ, et al., Assignment of the structural gene for argininosuccinate synthetase to proximal mouse chromosome 2. Genomics. 1990 Mar;6(3):545-7
RI	RI/RC Set: AKXL	2	J:10442 Jackson MJ, et al., Assignment of the structural gene for argininosuccinate synthetase to proximal mouse chromosome 2. Genomics. 1990 Mar;6(3):545-7
RI	RI/RC Set: SWXL	2	J:16092 Malek TR, et al., The IL-2 receptor beta chain gene (Il-2rb) is closely linked to the Pdgfb locus on mouse chromosome 15. Immunogenetics. 1993;38(2):154-6
RI	RI/RC Set: BXD	2	J:11420 Malo D, et al., Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2. Genomics. 1991 Jul;10(3):666-72
RI	RI/RC Set: SWXL	2	J:6960 Meruelo D, et al., Evidence for a major cluster of lymphocyte differentiation antigens on murine chromosome 2. Proc Natl Acad Sci U S A. 1982 Dec;79(23):7460-4
RI	RI/RC Set: CcS	2	J:11622 Moen CJ, et al., The recombinant congenic strains--a novel genetic tool applied to the study of colon tumor development in the mouse. Mamm Genome. 1991;1(4):217-27
RI	RI/RC Set: SMXA	2	J:30437 Nishimura M, et al., The SMXA: a new set of recombinant inbred strain of mice consisting of 26 substrains and their genetic profile. Mamm Genome. 1995 Dec;6(12):850-7
RI	RI/RC Set: AKXL	2	J:1901 Schurr E, et al., Mapping of the gene coding for the muscle protein nebulin (Neb) to the proximal region of mouse chromosome 2. Cytogenet Cell Genet. 1991;57(4):214-6
RI	RI/RC Set: BXD	2	J:1901 Schurr E, et al., Mapping of the gene coding for the muscle protein nebulin (Neb) to the proximal region of mouse chromosome 2. Cytogenet Cell Genet. 1991;57(4):214-6
RI	RI/RC Set: CcS	2	J:31555 Stassen AP, et al., Genetic composition of the recombinant congenic strains. Mamm Genome. 1996 Jan;7(1):55-8
RI	RI/RC Set: SWXJ	2	J:30436 Svenson KL, et al., Strain distribution pattern for SSLP markers in the SWXJ recombinant inbred strain set: chromosomes 1 to 6. Mamm Genome. 1995 Dec;6(12):867-72
TEXT		2	J:58906 Kandli M, et al., Isolation and characterization of two evolutionarily conserved murine kinases (Nek6 and nek7) related to the fungal mitotic regulator, NIMA. Genomics. 2000 Sep 1;68(2):187-96
TEXT		2	J:134111 Mori L, et al., Genetic control of susceptibility to collagen-induced arthritis in T cell receptor beta-chain transgenic mice. Arthritis Rheum. 1998 Feb;41(2):256-62
TEXT-Congenic		2	J:31355 Moen CJ, et al., Fine mapping of colon tumor susceptibility (Scc) genes in the mouse, different from the genes known to be somatically mutated in colon cancer. Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1082-6
TEXT-Genetic Cross		2	J:44 Moen CJ, et al., Scc-1, a novel colon cancer susceptibility gene in the mouse: linkage to CD44 (Ly-24, Pgp-1) on chromosome 2. Oncogene. 1992 Mar;7(3):563-6
TEXT-QTL		2	J:94347 Bauer K, et al., Identification of new quantitative trait loci in mice with collagen-induced arthritis. Arthritis Rheum. 2004 Nov;50(11):3721-8
TEXT-QTL		2	J:248997 Boon AC, et al., Host genetic variation affects resistance to infection with a highly pathogenic H5N1 influenza A virus in mice. J Virol. 2009 Oct;83(20):10417-26
TEXT-QTL		2	J:3240 Brownstein DG, et al., Serial backcross analysis of genetic resistance to mousepox, using marker loci for Rmp-2 and Rmp-3. J Virol. 1992 Dec;66(12):7073-9
TEXT-QTL		2	J:11032 Brownstein DG, et al., Chromosomal locations and gonadal dependence of genes that mediate resistance to ectromelia (mousepox) virus-induced mortality. J Virol. 1991 Apr;65(4):1946-51
TEXT-QTL		2	J:66641 Ewart SL, et al., Quantitative trait loci controlling allergen-induced airway hyperresponsiveness in inbred mice. Am J Respir Cell Mol Biol. 2000 Oct;23(4):537-45
TEXT-QTL		2	J:7345 Gervais F, et al., Genetic control of resistance to Listeria monocytogenes: regulation of leukocyte inflammatory responses by the Hc locus. J Immunol. 1984 Apr;132(4):2078-83
TEXT-QTL		2	J:100159 Hillebrandt S, et al., Complement factor 5 is a quantitative trait gene that modifies liver fibrogenesis in mice and humans. Nat Genet. 2005 Aug;37(8):835-43
TEXT-QTL		2	J:70882 Ji H, et al., Genetic influences on the end-stage effector phase of arthritis. J Exp Med. 2001 Aug 6;194(3):321-30
TEXT-QTL		2	J:69981 Johansson AC, et al., Genetic control of collagen-induced arthritis in a cross with NOD and C57BL/10 mice is dependent on gene regions encoding complement factor 5 and FcgammaRIIb and is not associated with loci controlling diabetes. Eur J Immunol. 2001 Jun;31(6):1847-56
TEXT-QTL		2	J:99793 Mazon Pelaez I, et al., Identification of quantitative trait loci controlling cortical motor evoked potentials in experimental autoimmune encephalomyelitis: correlation with incidence, onset and severity of disease. Hum Mol Genet. 2005 Jul 15;14(14):1977-89
TEXT-QTL		2	J:53356 McIndoe RA, et al., Localization of non-Mhc collagen-induced arthritis susceptibility loci in DBA/1j mice. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2210-4
TEXT-QTL		2	J:114155 Rangnekar AS, et al., Quantitative trait loci analysis of mice administered the methionine-choline deficient dietary model of experimental steatohepatitis. Liver Int. 2006 Oct;26(8):1000-5
TEXT-QTL		2	J:9501 Welkos SL, et al., Pathogenesis and genetic control of resistance to the Sterne strain of Bacillus anthracis. Microb Pathog. 1988 Jan;4(1):53-69
TEXT-QTL		2	J:116665 Yu X, et al., Fine mapping of collagen-induced arthritis quantitative trait loci in an advanced intercross line. J Immunol. 2006 Nov 15;177(10):7042-9
TEXT-QTL-Candidate Genes		2	J:108211 Karp CL, et al., Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma. Nat Immunol. 2000 Sep;1(3):221-6