Mapping Data Summary

• Symbol: Pcsk2
• Name: proprotein convertase subtilisin/kexin type 2
• ID: MGI:97512
• Chromosome: 2

16 mapping experiments

Experiment Type	Details	Chromosome	Reference
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	2	J:1676 Copeland NG, et al., Regional localization of three convertases, PC1 (Nec-1), PC2 (Nec-2), and furin (Fur), on mouse chromosomes. Genomics. 1992 Aug;13(4):1356-8
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	2	J:18309 Hess EJ, et al., Deletion map of the coloboma (Cm) locus on mouse chromosome 2. Genomics. 1994 May 1;21(1):257-61
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	2	J:35909 Lock LF, et al., The Cdc25 genes map to mouse chromosomes 2, 9, and 18. Mamm Genome. 1996 Oct;7(10):771-2
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	2	J:80573 Wang CC, et al., Conserved linkage of NK-2 homeobox gene pairs Nkx2-2/2-4 and Nkx2-1/2-9 in mammals. Mamm Genome. 2000 Jun;11(6):466-8
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	2	J:15563 Wilkie TM, et al., Identification, chromosomal location, and genome organization of mammalian G-protein-coupled receptors. Genomics. 1993 Nov;18(2):175-84
IN SITU	Band: F3-H2	2	J:11129 Seidah NG, et al., Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2. Mol Endocrinol. 1991 Jan;5(1):111-22
TEXT-Congenic		2	J:127206 Chiu S, et al., Identification of positional candidate genes for body weight and adiposity in subcongenic mice. Physiol Genomics. 2007 Sep 19;31(1):75-85
TEXT-Congenic		2	J:90700 Diament AL, et al., A novel mouse Chromosome 2 congenic strain with obesity phenotypes. Mamm Genome. 2004 Jun;15(6):452-9
TEXT-Genetic Cross		2	J:18309 Hess EJ, et al., Deletion map of the coloboma (Cm) locus on mouse chromosome 2. Genomics. 1994 May 1;21(1):257-61
TEXT-Genetic Cross		2	J:32426 Zuberi AR, et al., A genetic linkage map of mouse chromosome 2 extending from thrombospondin to paired box gene 1, including the H3 minor histocompatibility complex. Genomics. 1996 Apr 1;33(1):75-84
TEXT-Physical Mapping		2	J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
TEXT-QTL		2	J:62933 Kayo T, et al., Identification of two chromosomal loci determining glucose intolerance in a C57BL/6 mouse strain. Comp Med. 2000 Jun;50(3):296-302
TEXT-QTL		2	J:48038 Mehrabian M, et al., Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model. J Clin Invest. 1998 Jun 1;101(11):2485-96
TEXT-QTL		2	J:90699 Warden CH, et al., Identification of a congenic mouse line with obesity and body length phenotypes. Mamm Genome. 2004 Jun;15(6):460-71
TEXT-QTL-Candidate Genes		2	J:105312 MacLaren EJ, et al., Expression profiling identifies novel candidate genes for ethanol sensitivity QTLs. Mamm Genome. 2006 Feb;17(2):147-56
TEXT-Radiation Hybrid		2	J:68900 The Jackson Laboratory Mouse Radiation Hybrid Database, Mouse T31 Radiation Hybrid Data Load. Database Release. 2004;