Mapping Data Summary

• Symbol: Shh
• Name: sonic hedgehog
• ID: MGI:98297
• Chromosome: 5

26 mapping experiments

Experiment Type	Details	Chromosome	Reference
CROSS	Cross Type: Backcross Mapping Panel: Seldin	5	J:21621 Chang DT, et al., Products, genetic linkage and limb patterning activity of a murine hedgehog gene. Development. 1994 Nov;120(11):3339-53
CROSS	Cross Type: Backcross	5	J:9764 Cheng SV, et al., Synteny on mouse chromosome 5 of homologs for human DNA loci linked to the Huntington disease gene. Genomics. 1989 Apr;4(3):419-26
CROSS	Cross Type: Backcross	5	J:9764 Cheng SV, et al., Synteny on mouse chromosome 5 of homologs for human DNA loci linked to the Huntington disease gene. Genomics. 1989 Apr;4(3):419-26
CROSS	Cross Type: Backcross	5	J:63394 Clark RM, et al., A novel candidate gene for mouse and human preaxial polydactyly with altered expression in limbs of Hemimelic extra-toes mutant mice. Genomics. 2000 Jul 1;67(1):19-27
CROSS	Cross Type: Backcross	5	J:68687 Heus HC, et al., Hemimelic extra toes and Hammer toe are distinct mutations that show a genetic interaction. Mamm Genome. 2001 Jan;12(1):77-9
CROSS	Cross Type: Backcross	5	J:7357 Kozak CA, et al., A unique sequence related to the ecotropic murine leukemia virus is associated with the Fv-4 resistance gene. Proc Natl Acad Sci U S A. 1984 Feb;81(3):834-7
CROSS	Cross Type: Backcross	5	J:6689 Kozak CA, et al., Genetic mapping of ecotropic murine leukemia virus-inducing loci in six inbred strains. J Exp Med. 1982 Feb 1;155(2):524-34
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	5	J:27750 Marigo V, et al., Cloning, expression, and chromosomal location of SHH and IHH: two human homologues of the Drosophila segment polarity gene hedgehog. Genomics. 1995 Jul 1;28(1):44-51
CROSS	Cross Type: Backcross	5	J:10340 Martin GR, et al., Mapping of the two mouse engrailed-like genes: close linkage of En-1 to dominant hemimelia (Dh) on chromosome 1 and of En-2 to hemimelic extra-toes (Hx) on chromosome 5. Genomics. 1990 Feb;6(2):302-8
CROSS	Cross Type: Backcross	5	J:10340 Martin GR, et al., Mapping of the two mouse engrailed-like genes: close linkage of En-1 to dominant hemimelia (Dh) on chromosome 1 and of En-2 to hemimelic extra-toes (Hx) on chromosome 5. Genomics. 1990 Feb;6(2):302-8
CROSS	Cross Type: Backcross	5	J:19181 Robert B, et al., Msx1 is close but not allelic to either Hm or Hx on mouse chromosome 5. Mamm Genome. 1994 Jul;5(7):446-9
CROSS	Cross Type: Backcross	5	J:19181 Robert B, et al., Msx1 is close but not allelic to either Hm or Hx on mouse chromosome 5. Mamm Genome. 1994 Jul;5(7):446-9
CROSS	Cross Type: Backcross	5	J:19181 Robert B, et al., Msx1 is close but not allelic to either Hm or Hx on mouse chromosome 5. Mamm Genome. 1994 Jul;5(7):446-9
TEXT-Genetic Cross		5	J:68687 Heus HC, et al., Hemimelic extra toes and Hammer toe are distinct mutations that show a genetic interaction. Mamm Genome. 2001 Jan;12(1):77-9
TEXT-Genetic Cross		5	J:55926 Isobe T, et al., F. Genetic Strains Research Center. Analysis of the genetic structure of Pb hotspot in the Class II of MHC. Natl Inst Genet Jpn Annual Report. 1997;48:87-101
TEXT-Genetic Cross		5	J:27750 Marigo V, et al., Cloning, expression, and chromosomal location of SHH and IHH: two human homologues of the Drosophila segment polarity gene hedgehog. Genomics. 1995 Jul 1;28(1):44-51
TEXT-Genetic Cross		5	J:87798 Sagai T, et al., Phylogenetic conservation of a limb-specific, cis-acting regulator of Sonic hedgehog ( Shh). Mamm Genome. 2004 Jan;15(1):23-34
TEXT-Physical Mapping		5	J:63394 Clark RM, et al., A novel candidate gene for mouse and human preaxial polydactyly with altered expression in limbs of Hemimelic extra-toes mutant mice. Genomics. 2000 Jul 1;67(1):19-27
TEXT-Physical Mapping		5	J:84551 Lettice LA, et al., A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly. Hum Mol Genet. 2003 Jul 15;12(14):1725-35
TEXT-Physical Mapping		5	J:87798 Sagai T, et al., Phylogenetic conservation of a limb-specific, cis-acting regulator of Sonic hedgehog ( Shh). Mamm Genome. 2004 Jan;15(1):23-34
TEXT-Physical Mapping		5	J:63451 Schimenti JC, et al., Interdigitated deletion complexes on mouse chromosome 5 induced by irradiation of embryonic stem cells. Genome Res. 2000 Jul;10(7):1043-50
TEXT-Physical Mapping		5	J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
TEXT-QTL		5	J:78471 Leamy LJ, et al., Pleiotropy of quantitative trait loci for organ weights and limb bone lengths in mice. Physiol Genomics. 2002 Jul 12;10(1):21-9
TEXT-QTL		5	J:237754 Maga AM, et al., Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico. Front Physiol. 2015;6:92
TEXT-QTL		5	J:244712 Navarro N, et al., Does 3D Phenotyping Yield Substantial Insights in the Genetics of the Mouse Mandible Shape?. G3 (Bethesda). 2016 May 03;6(5):1153-63
TEXT-Radiation Hybrid		5	J:68900 The Jackson Laboratory Mouse Radiation Hybrid Database, Mouse T31 Radiation Hybrid Data Load. Database Release. 2004;