About   Help   FAQ
Dcaf8l Gene Detail
Summary
  • Symbol
    Dcaf8l
  • Name
    DDB1 and CUL4 associated factor 8 like
  • Synonyms
    PC231, PC326, Pet2, Pex3
Location &
Maps
more
  • Sequence Map
    ChrX:88447454-88453295 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 39.95 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    209 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_101758
 protein coding gene ChrX:88447454-88453295 (-)
129S1/SvImJ ENSMUSG00200031497
 protein coding gene ChrX:70460728-70466569 (-)
A/J ENSMUSG00195030235
 protein coding gene ChrX:74178628-74184471 (-)
AKR/J ENSMUSG00220027502
 protein coding gene ChrX:69068002-69073845 (-)
BALB/cJ ENSMUSG00180023901
 protein coding gene ChrX:70729374-70735217 (-)
C3H/HeJ ENSMUSG00175018519
 protein coding gene ChrX:74359177-74365019 (-)
C57BL/6NJ ENSMUSG00215013799
 protein coding gene ChrX:70877300-70883141 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033223
 protein coding gene ChrX:84271317-84276537 (-)
CAST/EiJ ENSTCUG00005027204
 protein coding gene ChrX:71958351-71964178 (-)
CBA/J ENSMUSG00210034253
 protein coding gene ChrX:71073980-71079821 (-)
DBA/2J ENSMUSG00185030901
 protein coding gene ChrX:83404378-83410218 (-)
FVB/NJ ENSMUSG00205018261
 protein coding gene ChrX:70366763-70372604 (-)
JF1/MsJ ENSUMUG00000019795
 protein coding gene ChrX:104245776-104251609 (-)
LP/J ENSMUSG00230009510
 protein coding gene ChrX:90063793-90069634 (-)
NOD/ShiLtJ ENSMUSG00190024830
 protein coding gene ChrX:70412806-70418646 (-)
NZO/HlLtJ ENSMUSG00225045130
 protein coding gene ChrX:95194658-95200498 (-)
PWK/PhJ ENSLUMG00010033455
 protein coding gene ChrX:69918778-69924602 (-)
SPRET/EiJ ENSMSPG00010031598
 protein coding gene ChrX:73744087-73747053 (-)
WSB/EiJ ENSIUOG00005038902
 protein coding gene ChrX:70980482-70986324 (-)



Homology
more
  • Human Ortholog
    DCAF8L1, DDB1 and CUL4 associated factor 8 like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DCAF8L1, DDB1 and CUL4 associated factor 8 like 1
  • Synonyms
    WDR42B
  • Links
    NCBI Gene ID: 139425
    UniProt: A6NGE4

  • Chr Location
    Xp21.3; chrX:27977992-27981449 (-)  GRCh38
  • Human Ortholog
    DCAF8L2, DDB1 and CUL4 associated factor 8 like 2
  • Synonyms
    WDR42C
  • Links
    NCBI Gene ID: 347442
    UniProt: P0C7V8

  • Chr Location
    Xp21.3; chrX:27468941-27749942 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 18630 NCBI Gene Model | MGI Sequence Detail 5842 C57BL/6J ±  kb
transcript NM_008821 RefSeq | MGI Sequence Detail 4182 C57BL/6  
polypeptide NP_032847 RefSeq | MGI Sequence Detail 747 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR045151 DDB1- and CUL4-associated factor 8-like
    IPR001680 WD40 repeat
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
less
  • All nucleic 4
    Genomic 1
    cDNA 3

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-18564, MGI:6324664
References
more
  • Summaries
    All 21
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:10429 Timblin C, et al., Application for PCR technology to subtractive cDNA cloning: identification of genes expressed specifically in murine plasmacytoma cells. Nucleic Acids Res. 1990 Mar 25;18(6):1587-93
  • Latest
    J:3100 Bergsagel PL, et al., Sequence and expression of a murine cDNA encoding PC326, a novel gene expressed in plasmacytomas but not normal plasma cells. Oncogene. 1992 Oct;7(10):2059-64
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory