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Sntb1 Gene Detail
Summary
  • Symbol
    Sntb1
  • Name
    syntrophin, basic 1
  • Synonyms
    59-1 DAP, beta1-Syntrophin
  • Feature Type
    protein coding gene
  • IDs
    MGI:101781
    NCBI Gene: 20649
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:55499784-55770345 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 22.14 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6830 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_101781
 protein coding gene Chr15:55499784-55770707 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021858
 protein coding gene Chr15:54734762-55009161 (-)
A/J MGP_AJ_G0021818
 protein coding gene Chr15:52573415-52842419 (-)
AKR/J MGP_AKRJ_G0021799
 protein coding gene Chr15:54065541-54337302 (-)
BALB/cJ MGP_BALBcJ_G0021825
 protein coding gene Chr15:52793065-53059466 (-)
C3H/HeJ MGP_C3HHeJ_G0021599
 protein coding gene Chr15:54146304-54421323 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022264
 protein coding gene Chr15:56854856-57144665 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019801
 protein coding gene Chr15:49791710-50052088 (-)
CAST/EiJ MGP_CASTEiJ_G0021116
 protein coding gene Chr15:54748036-55019823 (-)
CBA/J MGP_CBAJ_G0021568
 protein coding gene Chr15:58839998-59138756 (-)
DBA/2J MGP_DBA2J_G0021692
 protein coding gene Chr15:52466170-52715452 (-)
FVB/NJ MGP_FVBNJ_G0021670
 protein coding gene Chr15:51583448-51847477 (-)
LP/J MGP_LPJ_G0021762
 protein coding gene Chr15:54535210-54820900 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021694
 protein coding gene Chr15:63939053-64222630 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022287
 protein coding gene Chr15:54442158-54706911 (-)
PWK/PhJ MGP_PWKPhJ_G0020861
 protein coding gene Chr15:52538053-52803535 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020698
 protein coding gene Chr15:54164903-54456882 (-)
WSB/EiJ MGP_WSBEiJ_G0021171
 protein coding gene Chr15:54382033-54654195 (-)



Homology
more
  • Human Ortholog
    SNTB1, syntrophin beta 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SNTB1, syntrophin beta 1
  • Synonyms
    59-DAP, A1B, BSYN2, DAPA1B, SNT2, SNT2B1, TIP-43
  • Links
    NCBI Gene ID: 6641
    neXtProt AC: NX_Q13884
    UniProt: Q13884

  • Chr Location
    8q24.12; chr8:120535745-120813273 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    716
  • Tissues
    6
  • cDNA Data
    5
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000060429 Ensembl Gene Model | MGI Sequence Detail 270562 C57BL/6J ±  kb
transcript ENSMUST00000039769 Ensembl | MGI Sequence Detail 4919 Not Applicable  
polypeptide ENSMUSP00000041294 Ensembl | MGI Sequence Detail 537 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 5
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-18589
References
more
  • Summaries
    All 54
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 11
    Phenotypes 21
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:323009 Rao SB, et al., Orchestrating aquaporin-4 and connexin-43 expression in brain: Differential roles of alpha1- and beta1-syntrophin. Biochim Biophys Acta Biomembr. 2021 Aug 1;1863(8):183616
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory