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Coq3 Gene Detail
Summary
  • Symbol
    Coq3
  • Name
    coenzyme Q3 methyltransferase
  • Synonyms
    C77934
  • Feature Type
    protein coding gene
  • IDs
    MGI:101813
    NCBI Gene: 230027
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:21879673-21912162 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 9.11 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    944 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_101813
 protein coding gene Chr4:21879646-21912163 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028094
 protein coding gene Chr4:18902479-18950767 (+)
A/J MGP_AJ_G0028052
 protein coding gene Chr4:18342691-18379971 (+)
AKR/J MGP_AKRJ_G0028017
 protein coding gene Chr4:18762123-18800579 (+)
BALB/cJ MGP_BALBcJ_G0028063
 protein coding gene Chr4:18401073-18436981 (+)
C3H/HeJ MGP_C3HHeJ_G0027793
 protein coding gene Chr4:18930782-18969822 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028506
 protein coding gene Chr4:19668812-19709692 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025848
 protein coding gene Chr4:17007172-17034284 (+)
CAST/EiJ MGP_CASTEiJ_G0027248
 protein coding gene Chr4:18702560-18738487 (+)
CBA/J MGP_CBAJ_G0027766
 protein coding gene Chr4:20235008-20271682 (+)
DBA/2J MGP_DBA2J_G0027909
 protein coding gene Chr4:18212135-18249804 (+)
FVB/NJ MGP_FVBNJ_G0027875
 protein coding gene Chr4:17925019-17957677 (+)
LP/J MGP_LPJ_G0028018
 protein coding gene Chr4:18978853-19017757 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027908
 protein coding gene Chr4:21461200-21501417 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028565
 protein coding gene Chr4:18721480-18762877 (+)
PWK/PhJ MGP_PWKPhJ_G0026968
 protein coding gene Chr4:18046587-18082160 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026797
 protein coding gene Chr4:18530877-18578589 (+)
WSB/EiJ MGP_WSBEiJ_G0027325
 protein coding gene Chr4:18712751-18744587 (+)



Homology
more
  • Human Ortholog
    COQ3, coenzyme Q3, methyltransferase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COQ3, coenzyme Q3, methyltransferase
  • Synonyms
    bA9819.1, DHHBMT, DHHBMTASE, UG0215E05
  • Links
    NCBI Gene ID: 51805
    neXtProt AC: NX_Q9NZJ6
    UniProt: Q9NZJ6

  • Chr Location
    6q16.2; chr6:99369401-99394195 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele die in utero.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    25
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    814
  • Tissues
    97
  • cDNA Data
    38
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028247 Ensembl Gene Model | MGI Sequence Detail 32490 C57BL/6J ±  kb
transcript ENSMUST00000029909 Ensembl | MGI Sequence Detail 2651 Not Applicable  
polypeptide ENSMUSP00000029909 Ensembl | MGI Sequence Detail 370 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 40
    cDNA 39
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-18631, MGI:2140664
References
more
  • Summaries
    All 49
    Developmental Gene Expression 3
    Gene Ontology 10
    Phenotypes 12
  • Earliest
    J:19686 Marbois BN, et al., Ubiquinone biosynthesis in eukaryotic cells: tissue distribution of mRNA encoding 3,4-dihydroxy-5-polyprenylbenzoate methyltransferase in the rat and mapping of the COQ3 gene to mouse chromosome 4. Arch Biochem Biophys. 1994 Aug 15;313(1):83-8
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory