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Klra2 Gene Detail
Summary
  • Symbol
    Klra2
  • Name
    killer cell lectin-like receptor, subfamily A, member 2
  • Synonyms
    Ly49b
  • Feature Type
    protein coding gene
  • IDs
    MGI:101906
    NCBI Gene: 16633
  • Member of
    Klra cluster
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:131196186-131224325 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 63.44 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    615 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_101906
 protein coding gene Chr6:131196186-131224679 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031365
 protein coding gene Chr6:135147743-135175478 (-)
A/J MGP_AJ_G0031342
 protein coding gene Chr6:129898067-129923412 (-)
AKR/J MGP_AKRJ_G0031270
 protein coding gene Chr6:133662745-133691768 (-)
BALB/cJ MGP_BALBcJ_G0031349
 protein coding gene Chr6:129572903-129597065 (-)
C3H/HeJ MGP_C3HHeJ_G0031072
 protein coding gene Chr6:133772396-133795190 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031807
 protein coding gene Chr6:138765492-138790203 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028944
 protein coding gene Chr6:128183223-128213099 (-)
CAST/EiJ MGP_CASTEiJ_G0030443
 protein coding gene Chr6:133678126-133714114 (-)
CBA/J MGP_CBAJ_G0031030
 protein coding gene Chr6:144086725-144114642 (-)
DBA/2J MGP_DBA2J_G0031190
 protein coding gene Chr6:128805022-128831863 (-)
FVB/NJ MGP_FVBNJ_G0031139
 protein coding gene Chr6:127707167-127731145 (-)
LP/J MGP_LPJ_G0031270
 protein coding gene Chr6:135454536-135482116 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031178
 protein coding gene Chr6:148008877-148045730 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031840
 protein coding gene Chr6:133550955-133576752 (-)
PWK/PhJ MGP_PWKPhJ_G0030163
 protein coding gene Chr6:127199894-127226914 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029991
 protein coding gene Chr6:131803208-131833365 (-)
WSB/EiJ MGP_WSBEiJ_G0030530
 protein coding gene Chr6:134125542-134153818 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030187 Ensembl Gene Model | MGI Sequence Detail 28140 C57BL/6J ±  kb
transcript ENSMUST00000088867 Ensembl | MGI Sequence Detail 1132 Not Applicable  
polypeptide ENSMUSP00000086252 Ensembl | MGI Sequence Detail 321 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    Genomic 12
    cDNA 7
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-18733
References
more
  • Summaries
    All 34
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:10723 Yokoyama WM, et al., Chromosomal location of the Ly-49 (A1, YE1/48) multigene family. Genetic association with the NK 1.1 antigen. J Immunol. 1990 Oct 1;145(7):2353-8
  • Latest
    J:209402 Mickiewicz KM, et al., Mutagenesis of Ly49B reveals key structural elements required for promiscuous binding to MHC class I molecules and new insights into the molecular evolution of Ly49s. J Immunol. 2014 Feb 15;192(4):1558-69
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory