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mt-Ta Gene Detail
Summary
  • Symbol
    mt-Ta
  • Name
    mitochondrially encoded tRNA alanine
  • Synonyms
    tRNA, tRNA-Ala, TrnA tRNA
  • Feature Type
    tRNA gene
  • IDs
    MGI:102491
    NCBI Gene: 17726
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrMT:5018-5086 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome MT, Syntenic
Strain
Comparison
more
  • SNPs within 2kb
    21 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102491
 tRNA gene ChrMT:5018-5086 (-)
129S1/SvImJ MGP_129S1SvImJ_G0000315
 tRNA gene Chr9:126129685-126129753 (+)
A/J MGP_AJ_G0000287
 tRNA gene Chr9:121301559-121301627 (+)
AKR/J MGP_AKRJ_G0000276
 tRNA gene Chr9:124561080-124561148 (+)
BALB/cJ MGP_BALBcJ_G0000281
 tRNA gene Chr9:121227002-121227070 (+)
C3H/HeJ MGP_C3HHeJ_G0000268
 tRNA gene Chr9:125002365-125002433 (+)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0000161
 tRNA gene Chr9:118446264-118446332 (+)
CAST/EiJ MGP_CASTEiJ_G0000261
 tRNA gene Chr9:125036804-125036872 (+)
CBA/J MGP_CBAJ_G0000262
 tRNA gene Chr9:134328486-134328554 (+)
DBA/2J MGP_DBA2J_G0000264
 tRNA gene Chr9:120754998-120755066 (+)
FVB/NJ MGP_FVBNJ_G0000276
 tRNA gene Chr9:119662426-119662494 (+)
LP/J MGP_LPJ_G0000320
 tRNA gene Chr9:126465552-126465620 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0000280
 tRNA gene Chr9:135177309-135177377 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0000389
 tRNA gene Chr9:125026282-125026350 (+)
PWK/PhJ MGP_PWKPhJ_G0000218
 tRNA gene Chr9:121209356-121209424 (+)
SPRET/EiJ MGP_SPRETEiJ_G0000201
 tRNA gene Chr9:125126596-125126664 (+)
WSB/EiJ MGP_WSBEiJ_G0000267
 tRNA gene Chr9:124864759-124864827 (+)



Homology
more
  • Human Ortholog
    TRNA, tRNA-Ala
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRNA, tRNA-Ala
  • Synonyms
    MTTA
  • Links
    NCBI Gene ID: 4553

  • Chr Location
    chrMT:5587-5655 (-)  GRCh38
Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from multigenic genotypes
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    70
Representative SequencesLengthStrain/SpeciesFlank
genomic 17726 NCBI Gene Model | MGI Sequence Detail 69 C57BL/6J ±  kb
For the selected sequence
Molecular
Reagents
less
  • All nucleic 52
    Other 52
Other
Accession IDs
less
MGD-MRK-19328
References
more
  • Summaries
    All 23
    Diseases 1
    Gene Ontology 1
    Phenotypes 10
  • Earliest
    J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
  • Latest
    J:345168 Kremer LS, et al., A role for BCL2L13 and autophagy in germline purifying selection of mtDNA. PLoS Genet. 2023 Jan;19(1):e1010573
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory