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Nat3 Gene Detail
Summary
  • Symbol
    Nat3
  • Name
    N-acetyltransferase 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:102537
    NCBI Gene: 17962
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr8:67976506-68001279 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 33.39 cM, cytoband B3.1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    858 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102537
 protein coding gene Chr8:67976506-68001279 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033658
 protein coding gene Chr8:67623083-67648320 (+)
A/J MGP_AJ_G0033640
 protein coding gene Chr8:64898480-64923634 (+)
AKR/J MGP_AKRJ_G0033565
 protein coding gene Chr8:66633666-66658409 (+)
BALB/cJ MGP_BALBcJ_G0033636
 protein coding gene Chr8:65075804-65100613 (+)
C3H/HeJ MGP_C3HHeJ_G0033346
 protein coding gene Chr8:67390766-67415644 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034153
 protein coding gene Chr8:70163891-70188657 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031100
 protein coding gene Chr8:59828409-59853310 (+)
CAST/EiJ MGP_CASTEiJ_G0032671
 protein coding gene Chr8:66815029-66844978 (+)
CBA/J MGP_CBAJ_G0033324
 protein coding gene Chr8:72796313-72821648 (+)
DBA/2J MGP_DBA2J_G0033478
 protein coding gene Chr8:64603807-64628512 (+)
FVB/NJ MGP_FVBNJ_G0033419
 protein coding gene Chr8:63781150-63805950 (+)
LP/J MGP_LPJ_G0033566
 protein coding gene Chr8:67715754-67742455 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033463
 protein coding gene Chr8:75451538-75476512 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034171
 protein coding gene Chr8:66951046-66977996 (+)
PWK/PhJ MGP_PWKPhJ_G0032380
 protein coding gene Chr8:63871964-63897025 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032216
 protein coding gene Chr8:65844961-65877466 (+)
WSB/EiJ MGP_WSBEiJ_G0032788
 protein coding gene Chr8:67318226-67342975 (+)



Homology
more
  • Human Ortholog
    NAT1, N-acetyltransferase 1
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NAT1, N-acetyltransferase 1
  • Synonyms
    AAC1, MNAT, NAT-1, NATI
  • Links
    NCBI Gene ID: 9
    neXtProt AC: NX_P18440
    UniProt: P18440

  • Chr Location
    8p22; chr8:18170467-18223689 (+)  GRCh38
  • Human Ortholog
    NAT2, N-acetyltransferase 2
  • Synonyms
    AAC2, NAT-2, PNAT
  • Links
    NCBI Gene ID: 10
    neXtProt AC: NX_P11245
    UniProt: P11245

  • Chr Location
    8p22; chr8:18386301-18401218 (+)  GRCh38
Human Diseases
more
  • Diseases
    29 with human NAT1,NAT2 associations

Human Disease Mouse Models
      
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Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Mice homozygous for a null mutation are viable and fertile with no gross abnormalities.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    9
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    4
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 17962 NCBI Gene Model | MGI Sequence Detail 24774 C57BL/6J ±  kb
transcript NM_008674 RefSeq | MGI Sequence Detail 1395 ZRU/MplStud  
polypeptide P50296 UniProt | EBI | MGI Sequence Detail 290 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    Genomic 4
    cDNA 4
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-19381
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:11825 Kelly SL, et al., Arylamine N-acetyl transferase in mice. Biochem Soc Trans. 1992 May;20(2):106S
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory