Tg(AMY1C)9257Mm
Transgene Detail

Summary

• Symbol: Tg(AMY1C)9257Mm
• Name: transgene insertion 9257, Miriam Meisler
• MGI ID: MGI:1889519
• Synonyms: Tg.9257, Tg9257, Tg(AMY1C)1Mm
• Transgene: Tg(AMY1C)9257Mm Location: unknown Genetic Position: Chr18, Syntenic
• Alliance: Tg(AMY1C)9257Mm page

Transgene origin

• Strain of Origin: (C57BL/6J x C3H)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(AMY1C)9257Mm expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  AMY1C (278)

  Amy1	(MGI:88019)
  Amy2a1	(MGI:104548)
  Amy2a2	(MGI:3711220)
  Amy2a3	(MGI:3714985)
  Amy2a4	(MGI:3711258)
  Amy2a5	(MGI:88020)

• Tg(AMY1C)9257Mm expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  AMY1C (278)

  Amy1	(MGI:88019)
  Amy2a1	(MGI:104548)
  Amy2a2	(MGI:3711220)
  Amy2a3	(MGI:3714985)
  Amy2a4	(MGI:3711258)
  Amy2a5	(MGI:88020)

• Mutation details: Mutation caused by insertion of a transgene containing the sequence from the human salivary amylase gene.
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

18 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Phenotype and chromosome location of this mouse is similar to the mouse mutant Twirler.

Transgene copy number was estimated to be between 20 and 32.

References

• Original: J:16317 Ting CN, et al., Insertional mutation on mouse chromosome 18 with vestibular and craniofacial abnormalities. Genetics. 1994 Jan;136(1):247-54
• All: 3 reference(s)