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Stx3 Gene Detail
Summary
  • Symbol
    Stx3
  • Name
    syntaxin 3
  • Synonyms
    Syn-3, syntaxin 3A, syntaxin 3B
  • Feature Type
    protein coding gene
  • IDs
    MGI:103077
    NCBI Gene: 20908
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:11752482-11796767 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 8.52 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1453 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103077
 protein coding gene Chr19:11752482-11798933 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024886
 protein coding gene Chr19:9165095-9211548 (-)
A/J MGP_AJ_G0024860
 protein coding gene Chr19:8652370-8697825 (-)
AKR/J MGP_AKRJ_G0024835
 protein coding gene Chr19:8976917-9031576 (-)
BALB/cJ MGP_BALBcJ_G0024860
 protein coding gene Chr19:8653740-8698314 (-)
C3H/HeJ MGP_C3HHeJ_G0024626
 protein coding gene Chr19:8876808-8925111 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025308
 protein coding gene Chr19:9615491-9666393 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022734
 protein coding gene Chr19:9239140-9282733 (-)
CAST/EiJ MGP_CASTEiJ_G0024099
 protein coding gene Chr19:8469697-8528198 (-)
CBA/J MGP_CBAJ_G0024600
 protein coding gene Chr19:9682464-9730947 (-)
DBA/2J MGP_DBA2J_G0024727
 protein coding gene Chr19:8615440-8661602 (-)
FVB/NJ MGP_FVBNJ_G0024694
 protein coding gene Chr19:8647280-8690570 (-)
LP/J MGP_LPJ_G0024814
 protein coding gene Chr19:9167005-9218540 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024721
 protein coding gene Chr19:9593012-9644966 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025356
 protein coding gene Chr19:8961252-9009724 (-)
PWK/PhJ MGP_PWKPhJ_G0023843
 protein coding gene Chr19:8083074-8126809 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023649
 protein coding gene Chr19:8135542-8187701 (-)
WSB/EiJ MGP_WSBEiJ_G0024161
 protein coding gene Chr19:8811361-8863149 (-)



Homology
more
  • Human Ortholog
    STX3, syntaxin 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STX3, syntaxin 3
  • Synonyms
    DIAR12, MVID2, RDMVID, STX3A
  • Links
    NCBI Gene ID: 6809
    neXtProt AC: NX_Q13277
    UniProt: Q13277

  • Chr Location
    11q12.1; chr11:59713456-59805882 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human STX3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 3 alleles in 4 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    90
  • GO References
    18
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    832
  • Tissues
    86
  • cDNA Data
    24
  • Literature Summary
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041488 Ensembl Gene Model | MGI Sequence Detail 44286 C57BL/6J ±  kb
transcript ENSMUST00000069285 Ensembl | MGI Sequence Detail 2810 Not Applicable  
polypeptide ENSMUSP00000069529 Ensembl | MGI Sequence Detail 289 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 34
    cDNA 28
    Primer pair 6

    Microarray probesets 11
Other
Accession IDs
less
MGD-MRK-23941, MGI:2147464, MGI:2147666, MGI:2147735
References
more
  • Summaries
    All 61
    Developmental Gene Expression 12
    Gene Ontology 18
    Phenotypes 11
  • Earliest
    J:26509 Ibaraki K, et al., Identification of four different forms of syntaxin 3. Biochem Biophys Res Commun. 1995 Jun 26;211(3):997-1005
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory