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Hoxb3os Gene Detail
Summary
  • Symbol
    Hoxb3os
  • Name
    homeobox B3 and homeobox B2, opposite strand
  • Synonyms
    Gm11530
Location &
Maps
more
  • Sequence Map
    Chr11:96233860-96244220 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 59.85 cM
Strain
Comparison
more
  • SNPs within 2kb
    192 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103211
 antisense lncRNA gene Chr11:96233803-96245517 (-)
129S1/SvImJ MGP_129S1SvImJ_G0003046
 antisense lncRNA gene Chr11:98656170-98667811 (-)
A/J MGP_AJ_G0003023
 antisense lncRNA gene Chr11:94627567-94639155 (-)
AKR/J MGP_AKRJ_G0003004
 antisense lncRNA gene Chr11:97554204-97566024 (-)
BALB/cJ MGP_BALBcJ_G0003010
 antisense lncRNA gene Chr11:95127043-95139227 (-)
C3H/HeJ MGP_C3HHeJ_G0002966
 antisense lncRNA gene Chr11:97684987-97696621 (-)
C57BL/6NJ MGP_C57BL6NJ_G0003152
 antisense lncRNA gene Chr11:101737089-101748878 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0002691
 antisense lncRNA gene Chr11:92114360-92125931 (-)
CAST/EiJ MGP_CASTEiJ_G0002936
 antisense lncRNA gene Chr11:98510506-98522110 (-)
CBA/J MGP_CBAJ_G0002963
 antisense lncRNA gene Chr11:105901734-105913394 (-)
DBA/2J MGP_DBA2J_G0002969
 antisense lncRNA gene Chr11:94194976-94206611 (-)
FVB/NJ MGP_FVBNJ_G0002988
 antisense lncRNA gene Chr11:93673632-93685242 (-)
LP/J MGP_LPJ_G0003045
 antisense lncRNA gene Chr11:99192083-99203702 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0002976
 antisense lncRNA gene Chr11:105897180-105909712 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0003156
 antisense lncRNA gene Chr11:97861132-97872788 (-)
PWK/PhJ MGP_PWKPhJ_G0002895
 antisense lncRNA gene Chr11:95146895-95158746 (-)
SPRET/EiJ MGP_SPRETEiJ_G0002840
 antisense lncRNA gene Chr11:97588732-97600323 (-)
WSB/EiJ MGP_WSBEiJ_G0002966
 antisense lncRNA gene Chr11:97751101-97762722 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice with a knock-out of isoform 1 exhibit increased cell proliferation in the kidney but normal kidney morphology and function.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    746
  • Tissues
    19
  • cDNA Data
    1
  • Literature Summary
    7
Sequences &
Gene Models
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  • All Sequences
    25
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 102632302 NCBI Gene Model | MGI Sequence Detail 10361 C57BL/6J ±  kb
transcript NR_155303 RefSeq | MGI Sequence Detail 685 ZRU/MplStud  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 7
    Genomic 1
    cDNA 2
    Primer pair 1
    Other 3

    Microarray probesets 1
Other
Accession IDs
less
MGD-MRK-24079, MGI:3649348
References
more
  • Summaries
    All 33
    Developmental Gene Expression 7
    Gene Ontology 1
    Phenotypes 17
  • Earliest
    J:15577 Swiatek PJ, et al., Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20. Genes Dev. 1993 Nov;7(11):2071-84
  • Latest
    J:345935 Weisser I, et al., Ablation of Long Noncoding RNA Hoxb3os Exacerbates Cystogenesis in Mouse Polycystic Kidney Disease. J Am Soc Nephrol. 2024 Jan 1;35(1):41-55
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory