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Cyp2c29 Gene Detail
Summary
  • Symbol
    Cyp2c29
  • Name
    cytochrome P450, family 2, subfamily c, polypeptide 29
  • Synonyms
    Ah-2, Ahh-1, AHOH, AHOHase, Cyp2c, P450-2C
  • Feature Type
    protein coding gene
  • IDs
    MGI:103238
    NCBI Gene: 13095
  • Alliance
    gene page
  • Transcription Start Sites
    31 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:39275541-39319157 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 33.91 cM, cytoband D2
  • Mapping Data
    29 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1098 from dbSNP Build 142
  • Strain Annotations
    17
  • RFLP
    8
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103238
 protein coding gene Chr19:39257849-39319157 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025100
 protein coding gene Chr19:38391856-38450333 (+)
A/J MGP_AJ_G0025076
 protein coding gene Chr19:36507012-36563742 (+)
AKR/J MGP_AKRJ_G0025044
 protein coding gene Chr19:37736625-37805813 (+)
BALB/cJ MGP_BALBcJ_G0025074
 protein coding gene Chr19:36610621-36675732 (+)
C3H/HeJ MGP_C3HHeJ_G0024833
 protein coding gene Chr19:37820504-37885541 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025515
 protein coding gene Chr19:39434850-39495486 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0024299
 protein coding gene Chr19:37616876-37673615 (+)
CBA/J MGP_CBAJ_G0024810
 protein coding gene Chr19:41352945-41417437 (+)
DBA/2J MGP_DBA2J_G0024942
 protein coding gene Chr19:36336876-36410257 (+)
FVB/NJ MGP_FVBNJ_G0024903
 protein coding gene Chr19:36174051-36235543 (+)
LP/J MGP_LPJ_G0025028
 protein coding gene Chr19:38452659-38510568 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024934
 protein coding gene Chr19:41052393-41129412 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025573
 protein coding gene Chr19:37827242-37886612 (+)
PWK/PhJ MGP_PWKPhJ_G0024051
 protein coding gene Chr19:36202657-36260045 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023851
 protein coding gene Chr19:36600553-36660935 (+)
WSB/EiJ MGP_WSBEiJ_G0024367
 protein coding gene Chr19:37931407-37988679 (+)



Homology
more
  • Human Ortholog
    CYP2C18, cytochrome P450 family 2 subfamily C member 18
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP2C18, cytochrome P450 family 2 subfamily C member 18
  • Synonyms
    CPCI, CYP2C, CYP2C17, P450-6B/29C, P450IIC17
  • Links
    NCBI Gene ID: 1562
    neXtProt AC: NX_P33260
    UniProt: P33260

  • Chr Location
    10q23.33; chr10:94683729-94736190 (+)  GRCh38
  • Human Ortholog
    CYP2C19, cytochrome P450 family 2 subfamily C member 19
  • Synonyms
    CPCJ, CYP2C, CYPIIC17, CYPIIC19, P450C2C, P450IIC19
  • Links
    NCBI Gene ID: 1557
    neXtProt AC: NX_P33261
    UniProt: P33261

  • Chr Location
    10q23.33; chr10:94762681-94855547 (+)  GRCh38
  • Human Ortholog
    CYP2C8, cytochrome P450 family 2 subfamily C member 8
  • Synonyms
    CPC8, CYP2C8DM, CYPIIC8, MP-12/MP-20
  • Links
    NCBI Gene ID: 1558
    neXtProt AC: NX_P10632
    UniProt: P10632

  • Chr Location
    10q23.33; chr10:95036772-95069497 (-)  GRCh38
  • Human Ortholog
    CYP2C9, cytochrome P450 family 2 subfamily C member 9
  • Synonyms
    CPC9, CYP2C, CYP2C10, CYPIIC9, P450-2C9, P450IIC9
  • Links
    NCBI Gene ID: 1559
    neXtProt AC: NX_P11712
    UniProt: P11712

  • Chr Location
    10q23.33; chr10:94938658-94990091 (+)  GRCh38
Human Diseases
more
  • Diseases
    21 with human CYP2C19,CYP2C8,CYP2C9 associations

Human Disease Mouse Models
      
IDs
IDs
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Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    40
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    832
  • Tissues
    110
  • cDNA Data
    145
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 13095 NCBI Gene Model | MGI Sequence Detail 43617 C57BL/6J ±  kb
transcript NM_007815 RefSeq | MGI Sequence Detail 1774 ZRU/MplStud  
polypeptide Q64458 UniProt | EBI | MGI Sequence Detail 490 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 152
    cDNA 148
    Primer pair 2
    Other 2

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-1200, MGD-MRK-1220, MGD-MRK-13110, MGD-MRK-2319, MGD-MRK-24113, MGI:2147480, MGI:2147488
References
more
  • Summaries
    All 67
    Developmental Gene Expression 4
    Gene Ontology 9
    Phenotypes 9
  • Earliest
    J:84316 Niwa A, et al., Genetic expression of aryl hydrocarbon hydroxylase activity in the mouse. Distinction between the 'responsive' homozygote and heterozygote at the Ah locus. Arch Biochem Biophys. 1975 Feb;166(2):559-64
  • Latest
    J:342868 Oguro A, et al., Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder. J Lipid Res. 2023 Nov;64(11):100458
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory