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Rpia Gene Detail
Summary
  • Symbol
    Rpia
  • Name
    ribose 5-phosphate isomerase A
  • Feature Type
    protein coding gene
  • IDs
    MGI:103254
    NCBI Gene: 19895
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:70742704-70769159 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 32.06 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    855 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103254
 protein coding gene Chr6:70742704-70769216 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030848
 protein coding gene Chr6:71183118-71217102 (-)
A/J MGP_AJ_G0030818
 protein coding gene Chr6:68468913-68494941 (-)
AKR/J MGP_AKRJ_G0030747
 protein coding gene Chr6:70440569-70468242 (-)
BALB/cJ MGP_BALBcJ_G0030829
 protein coding gene Chr6:68497142-68524962 (-)
C3H/HeJ MGP_C3HHeJ_G0030883
 protein coding gene Chr6:113794513-113825304 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031287
 protein coding gene Chr6:73066961-73098290 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028476
 protein coding gene Chr6:67655793-67681933 (-)
CAST/EiJ MGP_CASTEiJ_G0029937
 protein coding gene Chr6:70273205-70303684 (-)
CBA/J MGP_CBAJ_G0030516
 protein coding gene Chr6:75939261-75972903 (-)
DBA/2J MGP_DBA2J_G0030668
 protein coding gene Chr6:67843902-67871560 (-)
FVB/NJ MGP_FVBNJ_G0030621
 protein coding gene Chr6:67210581-67237554 (-)
LP/J MGP_LPJ_G0030747
 protein coding gene Chr6:71120844-71149736 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030656
 protein coding gene Chr6:79492859-79525845 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031313
 protein coding gene Chr6:70266843-70297541 (-)
PWK/PhJ MGP_PWKPhJ_G0029653
 protein coding gene Chr6:66701072-66728140 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029481
 protein coding gene Chr6:68992564-69023429 (-)
WSB/EiJ MGP_WSBEiJ_G0030019
 protein coding gene Chr6:70601728-70631922 (-)



Homology
more
  • Human Ortholog
    RPIA, ribose 5-phosphate isomerase A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPIA, ribose 5-phosphate isomerase A
  • Synonyms
    RPI, RPIAD
  • Links
    NCBI Gene ID: 22934
    neXtProt AC: NX_P49247
    UniProt: P49247

  • Chr Location
    2p11.2; chr2:88691673-88750929 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    810
  • Tissues
    98
  • cDNA Data
    32
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 19895 NCBI Gene Model | MGI Sequence Detail 26456 C57BL/6J ±  kb
    transcript NM_009075 RefSeq | MGI Sequence Detail 1789 ZRU/MplStud  
    polypeptide P47968 UniProt | EBI | MGI Sequence Detail 303 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 38
      Genomic 4
      cDNA 32
      Primer pair 2

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-24130
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 4
      Gene Ontology 6
      Phenotypes 9
    • Earliest
      J:322163 Gumaa KA, et al., The pentose phosphate pathway of glucose metabolism. Enzyme profiles and transient and steady-state content of intermediates of alternative pathways of glucose metabolism in Krebs ascites cells. Biochem J. 1969 Dec;115(5):1009-29
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory