T(16;17)43H Cytogenetic Marker Detail

Summary

• Symbol
  T(16;17)43H
• Name
  reciprocal translocation, Chr 16 and 17, Harwell 43
• Synonyms
  T43H

• Feature Type
  reciprocal chromosomal translocation
• IDs
  MGI:104215
  NCBI Gene: 21098

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 16, cytoband A

Human Diseases

• Diseases
  2 with T(16;17)43H mouse models

Human Disease

Mouse Models

chromosomal disease

IDs

chromosomal disease      

DOID:0080014

View 1 model

Mouse Models

Human Disease Modeled: chromosomal disease

Allelic Composition	Genetic Background	Reference	Phenotypes
T(16;17)43H/0	involves: 101 * C3H * PWD/Ph	J:97039	View

Down syndrome

IDs

Down syndrome      

DOID:14250
ICD10CM:Q90
ICD9CM:758.0
MESH:D004314
NCI:C2993
OMIM:190685
ORDO:870
UMLS_CUI:C0013080

View 1 model

Mouse Models

Human Disease Modeled: Down syndrome

Allelic Composition	Genetic Background	Reference	Phenotypes
T(16;17)43H/0	involves: 101 * C3H * PWD/Ph	J:208905	View

Click on a disease name to see all genes associated with that disease.

• Mutations/Alleles
  1 with disease annotations

• References
  2 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  6 phenotype references
  

• All Mutations and Alleles
  1
• Radiation induced
  1
• Find Mice (IMSR)
  1 strains or lines available

Sequences &
Gene Models

• NCBI Gene
  21098

Other
Accession IDs

MGD-MRK-25539

References

• Summaries
  All 12

  Diseases 2

  Phenotypes 6
• Earliest
  J:34742 Lyon MF, et al., Autosomal translocations causing male sterility and viable aneuploidy in the mouse. Cytogenetics. 1966;5:335-54
• Latest
  J:228970 Cloutier JM, et al., Histone H2AFX Links Meiotic Chromosome Asynapsis to Prophase I Oocyte Loss in Mammals. PLoS Genet. 2015 Oct;11(10):e1005462