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Amy2a1 Gene Detail
Summary
  • Symbol
    Amy2a1
  • Name
    amylase 2a1
  • Synonyms
    Amy2-1, mAmy2-6
  • Feature Type
    protein coding gene
  • IDs
    MGI:104548
    NCBI Gene: 100043207
  • Member of
    Amy cluster
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:113323052-113326077 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 49.35 cM
Strain
Comparison
more
  • SNPs within 2kb
    129 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104548
 protein coding gene Chr3:113314932-113326077 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027797
 protein coding gene Chr3:114910920-114914326 (-)
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0027499
 protein coding gene Chr3:114700777-114704091 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028214
 protein coding gene Chr3:119519196-119529844 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025553
 protein coding gene Chr3:107413427-107418916 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0027474
 protein coding gene Chr3:123243478-123370949 (-)
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0027725
 protein coding gene Chr3:116557141-116575237 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0028268
 protein coding gene Chr3:113556054-113664646 (-)
PWK/PhJ MGP_PWKPhJ_G0026681
 protein coding gene Chr3:110414203-110422122 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026502
 protein coding gene Chr3:111802025-111806912 (+)
WSB/EiJ MGP_WSBEiJ_G0027035
 protein coding gene Chr3:114547198-114550234 (-)



Homology
more
  • Human Ortholog
    AMY1A, amylase alpha 1A
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AMY2A, amylase alpha 2A
  • Synonyms
    AMY2, PA
  • Links
    NCBI Gene ID: 279
    neXtProt AC: NX_P04746
    UniProt: P04746

  • Chr Location
    1p21.1; chr1:103616651-103625780 (+)  GRCh38
  • Human Ortholog
    AMY2B, amylase alpha 2B
  • Synonyms
    AMY2, AMY3, HXA
  • Links
    NCBI Gene ID: 280
    neXtProt AC: NX_P19961
    UniProt: P19961

  • Chr Location
    1p21.1; chr1:103553815-103579534 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    21
  • RefSeq
    2
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000070360 Ensembl Gene Model | MGI Sequence Detail 3026 C57BL/6J ±  kb
transcript ENSMUST00000132353 Ensembl | MGI Sequence Detail 890 Not Applicable  
polypeptide ENSMUSP00000118962 Ensembl | MGI Sequence Detail 245 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 4
    Genomic 1
    cDNA 3
Other
Accession IDs
less
MGD-MRK-25980, MGI:3714988
References
more
  • Summaries
    All 27
    Diseases 1
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:6855 Strahler JR, et al., Two distinct pancreatic amylase genes are active in YBR mice. Genetics. 1982 May;101(1):91-102
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory