Bis1 QTL Detail

Summary

• Symbol
  Bis1
• Name
  beta-carboline-induced seizures 1

• Feature Type
  QTL
• IDs
  MGI:104794
  NCBI Gene: 110295

Location &
Maps

• Sequence Map
  Chr4:136864433-136864536 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 4, 69.44 cM (cM position of peak correlated region/marker)
• Mapping Data
  2 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  2 phenotype references
  

• All Mutations and Alleles
  4
• QTL
  4
• Find Mice (IMSR)
  0 strains or lines available

C57BL/6J carries the susceptible and A/J the resistance allele for this QTL for seizure response to a GABAA receptor inverse agonist.

Sequences &
Gene Models

• NCBI Gene
  110295

Other
Accession IDs

MGD-MRK-28086

References

• Summaries
  All 4

  Phenotypes 2
• Earliest
  J:28058 Martin B, et al., Mouse chromosomes 4 and 13 are involved in beta-carboline-induced seizures. J Hered. 1995 Jul-Aug;86(4):274-9
• Latest
  J:82183 Zerr P, et al., The murine Bis1 seizure gene and the Kcnab2 gene encoding the beta2-subunit of the K+ channel are different. Neurogenetics. 2000 Mar;2(4):231-4