Tic1 Other Genome Feature Detail

Summary

• Symbol
  Tic1
• Name
  transplantation-specific integration cluster 1
• Synonyms
  pim-2, Pim2

• Feature Type
  unclassified other genome feature
• IDs
  MGI:104869
  NCBI Gene: 111748

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 17, Syntenic
• Mapping Data
  12 experiments

Strain
Comparison

• RFLP
  4

Mutations,
Alleles, and
Phenotypes

This locus is a proviral integration site carrying somatically acquired proviruses. Integration occurs in a subpopulation of primary tumor cells, but these selectively grow out on transplantation. Tic1 insertion is a late event, often preceded by other proviral insertions.

Expression

• Other Mouse Links
  GEO

Sequences &
Gene Models

• NCBI Gene
  111748

Molecular
Reagents

• All nucleic 5

  Genomic 5

Other
Accession IDs

MGD-MRK-28166

References

• Summaries
  All 12
• Earliest
  J:9795 Breuer ML, et al., Evidence for the involvement of pim-2, a new common proviral insertion site, in progression of lymphomas. EMBO J. 1989 Mar;8(3):743-8
• Latest
  J:54668 Fujii T, et al., Sperizin is a murine RING zinc-finger protein specifically expressed in Haploid germ cells. Genomics. 1999 Apr 1;57(1):94-101