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Psma2 Gene Detail
Summary
  • Symbol
    Psma2
  • Name
    proteasome subunit alpha 2
  • Synonyms
    Lmpc3
  • Feature Type
    protein coding gene
  • IDs
    MGI:104885
    NCBI Gene: 19166
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:14787827-14800258 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 5.36 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    465 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104885
 protein coding gene Chr13:14787825-14848821 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020245
 protein coding gene Chr13:11599817-11612739 (+)
A/J MGP_AJ_G0020203
 protein coding gene Chr13:11507723-11523188 (+)
AKR/J MGP_AKRJ_G0020177
 protein coding gene Chr13:11656478-11669954 (+)
BALB/cJ MGP_BALBcJ_G0020189
 protein coding gene Chr13:11480202-11493181 (+)
C3H/HeJ MGP_C3HHeJ_G0019993
 protein coding gene Chr13:11794050-11805932 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020633
 protein coding gene Chr13:12225090-12241675 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018239
 protein coding gene Chr13:10204251-10215223 (+)
CAST/EiJ MGP_CASTEiJ_G0019526
 protein coding gene Chr13:11462852-11476008 (+)
CBA/J MGP_CBAJ_G0019957
 protein coding gene Chr13:12581177-12598673 (+)
DBA/2J MGP_DBA2J_G0020076
 protein coding gene Chr13:11158260-11170112 (+)
FVB/NJ MGP_FVBNJ_G0020057
 protein coding gene Chr13:10920731-10932446 (+)
LP/J MGP_LPJ_G0020146
 protein coding gene Chr13:11813477-11825264 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020094
 protein coding gene Chr13:12744303-12767722 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020660
 protein coding gene Chr13:11456403-11476818 (+)
PWK/PhJ MGP_PWKPhJ_G0019290
 protein coding gene Chr13:11237785-11250310 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019097
 protein coding gene Chr13:10613257-10624398 (+)
WSB/EiJ MGP_WSBEiJ_G0019588
 protein coding gene Chr13:11469373-11482113 (+)



Homology
more
  • Human Ortholog
    PSMA2, proteasome 20S subunit alpha 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PSMA2, proteasome 20S subunit alpha 2
  • Synonyms
    HC3, MU, PMSA2, PSC2
  • Links
    NCBI Gene ID: 5683
    neXtProt AC: NX_P25787
    UniProt: P25787

  • Chr Location
    7p14.1; chr7:42916828-42932185 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    214
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 19166 NCBI Gene Model | MGI Sequence Detail 12432 C57BL/6J ±  kb
transcript NM_008944 RefSeq | MGI Sequence Detail 963 C57BL/6  
polypeptide P49722 UniProt | EBI | MGI Sequence Detail 234 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 216
    cDNA 216

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-11825, MGD-MRK-29038
References
more
  • Summaries
    All 43
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 10
  • Earliest
    J:4568 Woodward EC, et al., Chromosomal mapping of the non-MHC linked proteasome genes. J Immunol. 1993;150(8):43A (Abstr.)
  • Latest
    J:338299 Xing L, et al., Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice. Cell Rep. 2023 Jun 28;42(7):112706
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory