t Gene Detail

Summary

• Symbol
  t
• Name
  t-complex

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:105076
  NCBI Gene: 20998
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 17, Syntenic
• Mapping Data
  23 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  49 phenotypes from 40 alleles in 10 genetic backgrounds
  52 phenotypes from multigenic genotypes
  121 phenotype references
  

• All Mutations and Alleles
  151
• Endonuclease-mediated
  1
• Radiation induced
  1
• Spontaneous
  95
• Transgenic
  7
• Genomic Mutations
  2 involving t
• Find Mice (IMSR)
  19 strains or lines available

Mice carrying a t haplotype and heterozygous for a dominant brachyury allele are tailless. Mice inheriting specific combinations of t haplotypes may show transmission ratio distortion, recombination suppression, male sterility, or lethality.

Expression

• Other Mouse Links
  GEO

Sequences &
Gene Models

• NCBI Gene
  20998

Other
Accession IDs

MGD-MRK-1684, MGD-MRK-32116, MGI:1203518, MGI:88217

References

• Summaries
  All 146

  Phenotypes 121
• Earliest
  J:176338 Chesley P, et al., The Inheritance of Taillessness (Anury) in the House Mouse. Genetics. 1936 Sep;21(5):525-36
• Latest
  J:326487 IMGC, Abstracts for the IMGC2022 meeting (October 2022). MGI Direct Data Submission. 2022;