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Tgoln1 Gene Detail
Summary
  • Symbol
    Tgoln1
  • Name
    trans-golgi network protein
  • Synonyms
    D6Ertd384e, TGN38, TGN38A, Ttgn1
  • Feature Type
    protein coding gene
  • IDs
    MGI:105080
    NCBI Gene: 22134
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:72585415-72593983 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 32.27 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    255 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105080
 protein coding gene Chr6:72585403-72593983 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030882
 protein coding gene Chr6:73179229-73188959 (-)
A/J MGP_AJ_G0030852
 protein coding gene Chr6:70337049-70345364 (-)
AKR/J MGP_AKRJ_G0030781
 protein coding gene Chr6:72409241-72419238 (-)
BALB/cJ MGP_BALBcJ_G0030863
 protein coding gene Chr6:70363564-70372885 (-)
C3H/HeJ MGP_C3HHeJ_G0030849
 protein coding gene Chr6:111824267-111832410 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031321
 protein coding gene Chr6:75092848-75101128 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028510
 protein coding gene Chr6:69476900-69484392 (-)
CAST/EiJ MGP_CASTEiJ_G0029971
 protein coding gene Chr6:72277845-72286032 (-)
CBA/J MGP_CBAJ_G0030550
 protein coding gene Chr6:78166790-78174944 (-)
DBA/2J MGP_DBA2J_G0030702
 protein coding gene Chr6:69728160-69736356 (-)
FVB/NJ MGP_FVBNJ_G0030655
 protein coding gene Chr6:69117456-69129328 (-)
LP/J MGP_LPJ_G0030781
 protein coding gene Chr6:73080635-73090696 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030690
 protein coding gene Chr6:81536612-81544742 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031347
 protein coding gene Chr6:72233193-72243329 (-)
PWK/PhJ MGP_PWKPhJ_G0029687
 protein coding gene Chr6:68643980-68652250 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029515
 protein coding gene Chr6:70974750-70982906 (-)
WSB/EiJ MGP_WSBEiJ_G0030053
 protein coding gene Chr6:72605871-72614032 (-)



Homology
more
  • Human Ortholog
    TGOLN2, trans-golgi network protein 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TGOLN2, trans-golgi network protein 2
  • Synonyms
    hTGN46, hTGN48, hTGN51, TGN38, TGN46, TGN48, TGN51, TTGN2
  • Links
    NCBI Gene ID: 10618
    neXtProt AC: NX_O43493
    UniProt: O43493

  • Chr Location
    2p11.2; chr2:85318027-85328251 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    716
  • Tissues
    3
  • cDNA Data
    18
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000056429 Ensembl Gene Model | MGI Sequence Detail 8569 C57BL/6J ±  kb
transcript ENSMUST00000070524 Ensembl | MGI Sequence Detail 5013 Not Applicable  
polypeptide ENSMUSP00000068487 Ensembl | MGI Sequence Detail 353 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 19
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-32120, MGI:1196440, MGI:2141549
References
more
  • Summaries
    All 50
    Developmental Gene Expression 6
    Gene Ontology 11
    Phenotypes 7
  • Earliest
    J:26092 Kasai K, et al., Strain-specific presence of two TGN38 isoforms and absence of TGN41 in mouse. J Biol Chem. 1995 Jun 16;270(24):14471-6
  • Latest
    J:342331 Hara Y, et al., ADP Ribosylation Factor 4 (Arf4) Regulates Radial Migration through N-Cadherin Trafficking during Cerebral Cortical Development. eNeuro. 2023 Nov;10(11):ENEURO.0125-23.2023
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory