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Mageb3 Gene Detail
Summary
  • Symbol
    Mageb3
  • Name
    MAGE family member B3
  • Synonyms
    Mage-b3, Mage-ps1, Mage-rs3, Smage3
  • Feature Type
    protein coding gene
  • IDs
    MGI:105109
    NCBI Gene: 17147
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr2:121784252-121786573 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 60.46 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    98 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105109
 protein coding gene Chr2:121784233-121786573 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0026362
 protein coding gene Chr2:119806950-119808289 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0026374
 protein coding gene Chr2:120046805-120048227 (-)
C3H/HeJ MGP_C3HHeJ_G0026120
 protein coding gene Chr2:123646397-123648992 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026822
 protein coding gene Chr2:128982792-128986331 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0026098
 protein coding gene Chr2:133514587-133517185 (-)
DBA/2J MGP_DBA2J_G0026235
 protein coding gene Chr2:119210493-119213463 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0026337
 protein coding gene Chr2:125169020-125171543 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026217
 protein coding gene Chr2:137733164-137736716 (-)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0025117
 protein coding gene Chr2:122444374-122446101 (-)
WSB/EiJ MGP_WSBEiJ_G0025652
 protein coding gene Chr2:124141082-124145263 (-)



Homology
more
  • Human Ortholog
    MAGEB1, MAGE family member B1
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAGEB1, MAGE family member B1
  • Synonyms
    CT3.1, DAM10, MAGEL1, MAGE-Xp
  • Links
    NCBI Gene ID: 4112
    neXtProt AC: NX_P43366
    UniProt: P43366

  • Chr Location
    Xp21.2; chrX:30243715-30252040 (+)  GRCh38
  • Human Ortholog
    MAGEB6, MAGE family member B6
  • Synonyms
    CT3.4, MAGE-B6, MAGEB6A
  • Links
    NCBI Gene ID: 158809
    neXtProt AC: NX_Q8N7X4
    UniProt: Q8N7X4

  • Chr Location
    Xp21.3; chrX:26192440-26195646 (+)  GRCh38
  • Human Ortholog
    MAGEB6B, MAGE family member B6B
  • Synonyms
    MAGEB6P1
  • Links
    NCBI Gene ID: 392433
    UniProt: A0A0J9YX57

  • Chr Location
    Xp21.3; chrX:26160601-26162410 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    4
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Mageb3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    20 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    769
  • Tissues
    42
  • cDNA Data
    4
  • Literature Summary
    11
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 17147 NCBI Gene Model | MGI Sequence Detail 2322 C57BL/6J ±  kb
transcript NM_008545 RefSeq | MGI Sequence Detail 2322 C57BL/6  
polypeptide NP_032571 RefSeq | MGI Sequence Detail 330 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR002190 MAGE homology domain
    IPR041898 MAGE homology domain, winged helix WH1 motif
    IPR041899 MAGE homology domain, winged helix WH2 motif
    IPR037445 Melanoma-associated antigen
Molecular
Reagents
less
  • All nucleic 8
    Genomic 2
    cDNA 4
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-32149
References
more
  • Summaries
    All 37
    Developmental Gene Expression 11
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:310310 Gordeeva O, et al., Expression dynamics of Mage family genes during self-renewal and differentiation of mouse pluripotent stem and teratocarcinoma cells. Oncotarget. 2019 May 14;10(35):3248-3266
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory