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Mageb2 Gene Detail
Summary
  • Symbol
    Mageb2
  • Name
    MAGE family member B2
  • Synonyms
    Mage-b2, Mage-rs2, Smage2
  • Feature Type
    protein coding gene
  • IDs
    MGI:105117
    NCBI Gene: 17146
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    ChrX:90375511-90376503 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 40.35 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    50 from dbSNP Build 142
  • Strain Annotations
    8
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105117
 protein coding gene ChrX:90375296-90376966 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035898
 protein coding gene ChrX:87598427-87602285 (+)
A/J MGP_AJ_G0035886
 protein coding gene ChrX:88488230-88489006 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0035864
 protein coding gene ChrX:86422558-86424218 (+)
C3H/HeJ MGP_C3HHeJ_G0035578
 protein coding gene ChrX:88714138-88715044 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036398
 protein coding gene ChrX:91045906-91070038 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0035705
 protein coding gene ChrX:86995732-86997078 (+)
FVB/NJ MGP_FVBNJ_G0035645
 protein coding gene ChrX:86413992-86414774 (+)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    MAGEB1, MAGE family member B1
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAGEB1, MAGE family member B1
  • Synonyms
    CT3.1, DAM10, MAGEL1, MAGE-Xp
  • Links
    NCBI Gene ID: 4112
    neXtProt AC: NX_P43366
    UniProt: P43366

  • Chr Location
    Xp21.2; chrX:30243715-30252040 (+)  GRCh38
  • Human Ortholog
    MAGEB6, MAGE family member B6
  • Synonyms
    CT3.4, MAGE-B6, MAGEB6A
  • Links
    NCBI Gene ID: 158809
    neXtProt AC: NX_Q8N7X4
    UniProt: Q8N7X4

  • Chr Location
    Xp21.3; chrX:26192440-26195646 (+)  GRCh38
  • Human Ortholog
    MAGEB6B, MAGE family member B6B
  • Synonyms
    MAGEB6P1
  • Links
    NCBI Gene ID: 392433
    UniProt: A0A0J9YX57

  • Chr Location
    Xp21.3; chrX:26160601-26162410 (+)  GRCh38
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    725
  • Tissues
    19
  • cDNA Data
    7
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 17146 NCBI Gene Model | MGI Sequence Detail 993 C57BL/6J ±  kb
transcript NM_031171 RefSeq | MGI Sequence Detail 993 DBA/2  
polypeptide NP_112448 RefSeq | MGI Sequence Detail 330 DBA/2  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 11
    Genomic 3
    cDNA 7
    Primer pair 1

    Microarray probesets 1
Other
Accession IDs
less
MGD-MRK-32157
References
more
  • Summaries
    All 14
    Developmental Gene Expression 2
    Gene Ontology 1
  • Earliest
    J:27405 De Backer O, et al., Structure, chromosomal location, and expression pattern of three mouse genes homologous to the human MAGE genes. Genomics. 1995 Jul 1;28(1):74-83
  • Latest
    J:297181 Lee AK, et al., Translational Repression of G3BP in Cancer and Germ Cells Suppresses Stress Granules and Enhances Stress Tolerance. Mol Cell. 2020 Aug 20;79(4):645-659.e9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory