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Eif1 Gene Detail
Summary
  • Symbol
    Eif1
  • Name
    eukaryotic translation initiation factor 1
  • Synonyms
    Sui1-rs1
  • Feature Type
    protein coding gene
  • IDs
    MGI:105125
    NCBI Gene: 20918
  • Alliance
    genome feature page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:100210775-100212925 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 63.46 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    123 from dbSNP Build 142
  • Strain Annotations
    15
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105125
 protein coding gene Chr11:100210711-100212925 (+)
129S1/SvImJ ENSMUSG00200050087
 protein coding gene Chr11:97481945-97484156 (+)
A/J ENSMUSG00195050494
 protein coding gene Chr11:97178856-97181074 (+)
AKR/J ENSMUSG00220050955
 protein coding gene Chr11:97416202-97418413 (+)
BALB/cJ ENSMUSG00180049679
 protein coding gene Chr11:97543776-97545987 (+)
C3H/HeJ ENSMUSG00175051403
 protein coding gene Chr11:97455501-97457712 (+)
C57BL/6NJ ENSMUSG00215053077
 protein coding gene Chr11:97029693-97031904 (+)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005048485
 protein coding gene Chr11:96962930-96965151 (+)
CBA/J ENSMUSG00210051687
 protein coding gene Chr11:97177137-97179348 (+)
DBA/2J ENSMUSG00185046079
 protein coding gene Chr11:97505383-97507594 (+)
FVB/NJ ENSMUSG00205048128
 protein coding gene Chr11:97360602-97362813 (+)
JF1/MsJ ENSUMUG00000035613
 protein coding gene Chr11:97755993-97758212 (+)
LP/J ENSMUSG00230044970
 protein coding gene Chr11:98558108-98560319 (+)
NOD/ShiLtJ ENSMUSG00190044885
 protein coding gene Chr11:97540173-97542384 (+)
NZO/HlLtJ ENSMUSG00225051379
 protein coding gene Chr11:100593959-100596170 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    EIF1, eukaryotic translation initiation factor 1
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EIF1, eukaryotic translation initiation factor 1
  • Synonyms
    A121, EIF-1, EIF1A, ISO1, SUI1
  • Links
    NCBI Gene ID: 10209
    UniProt: P41567

  • Chr Location
    17q21.2; chr17:41688883-41692668 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    631
  • Tissues
    13
  • cDNA Data
    477
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 20918 NCBI Gene Model | MGI Sequence Detail 2151 C57BL/6J ±  kb
transcript NM_011508 RefSeq | MGI Sequence Detail 1279 C57BL/6  
polypeptide P48024 UniProt | EBI | MGI Sequence Detail 113 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 479
    cDNA 478
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-32166
References
more
  • Summaries
    All 43
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 15
  • Earliest
    J:30847 Purohit R, et al., Multiple translation initiation factor Sui1 related sequences in mammalian genomes. Mamm Genome. 1996 Jan;7(1):79-80
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory