Sle2 QTL Detail

Summary

• Symbol
  Sle2
• Name
  systemic lupus erythmatosus susceptibility 2

• Feature Type
  QTL
• IDs
  MGI:105963
  NCBI Gene: 112366

Location &
Maps

• Sequence Map
  Chr4:94957579-94957775 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 4, 39.40 cM (cM position of peak correlated region/marker)
• Mapping Data
  2 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  2 phenotypes from multigenic genotypes
  25 phenotype references
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  1 strains or lines available

Sequences &
Gene Models

• NCBI Gene
  112366

Other
Accession IDs

MGD-MRK-33642

References

• Summaries
  All 39

  Phenotypes 25
• Earliest
  J:25006 Morel L, et al., Polygenic control of susceptibility to murine systemic lupus erythematosus. Immunity. 1994 Jun;1(3):219-29
• Latest
  J:355704 Wang Z, et al., Egr2 Deletion in Autoimmune-Prone C57BL6/lpr Mice Suppresses the Expression of Methylation-Sensitive Dlk1-Dio3 Cluster MicroRNAs. Immunohorizons. 2023 Dec 1;7(12):898-907