Rpl26 MGI Mouse Gene Detail - MGI:106022

Symbol

Rpl26
Name

ribosomal protein L26
Synonyms

SIG-20

Feature Type

protein coding gene
IDs

MGI:106022
NCBI Gene: 19941
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr11:68792392-68795360 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 42.17 cM, cytoband B3
Mapping Data

1 experiment

SNPs within 2kb

246 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_106022	protein coding gene	Chr11:68792392-68797815 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0018507	protein coding gene	Chr11:69283809-69290281 (+)
A/J	MGP_AJ_G0018476	protein coding gene	Chr11:66688334-66694850 (+)
AKR/J	MGP_AKRJ_G0018445	protein coding gene	Chr11:68678461-68685859 (+)
BALB/cJ	MGP_BALBcJ_G0018447	protein coding gene	Chr11:66983977-66989684 (+)
C3H/HeJ	MGP_C3HHeJ_G0018260	protein coding gene	Chr11:68700958-68706666 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0018899	protein coding gene	Chr11:71390853-71396250 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0016543	protein coding gene	Chr11:63626507-63632533 (+)
CAST/EiJ	MGP_CASTEiJ_G0017816	protein coding gene	Chr11:68935476-68940876 (+)
CBA/J	MGP_CBAJ_G0018234	protein coding gene	Chr11:74565148-74575221 (+)
DBA/2J	MGP_DBA2J_G0018343	protein coding gene	Chr11:66285175-66290481 (+)
FVB/NJ	MGP_FVBNJ_G0018333	protein coding gene	Chr11:65906913-65912319 (+)
LP/J	MGP_LPJ_G0018414	protein coding gene	Chr11:69864690-69870884 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0018356	protein coding gene	Chr11:75243491-75251337 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0018940	protein coding gene	Chr11:68922772-68930054 (+)
PWK/PhJ	MGP_PWKPhJ_G0017591	protein coding gene	Chr11:66912280-66917936 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0017379	protein coding gene	Chr11:68756410-68762046 (+)
WSB/EiJ	MGP_WSBEiJ_G0017869	protein coding gene	Chr11:68561567-68567097 (+)

Human Ortholog

RPL26, ribosomal protein L26

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RPL26, ribosomal protein L26
Synonyms

DBA11, L26, uL24
Links

HGNC:10327

NCBI Gene ID: 6154

neXtProt AC: NX_P61254

UniProt: P61254
Chr Location

17p13.1; chr17:8377516-8383213 (-) GRCh38

MGI Vertebrate Homology

Rpl26 stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: RPL26
Gene Tree

Rpl26

Diseases

1 with human RPL26 associations

				Human Disease	Mouse Models
				Diamond-Blackfan anemia 11 IDs Diamond-Blackfan anemia 11 DOID:0111892 OMIM:614900

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

9 phenotype references

All Mutations and Alleles

9
Chemically induced (other)

1
Gene trapped

7
Targeted

1
Genomic Mutations

1 involving Rpl26
Incidental Mutations

APF , CvDC
Find Mice (IMSR)

5 strains or lines available

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All GO Annotations

50
GO References

9

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

714
Tissues

4
cDNA Data

12
Literature Summary

4

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase rpl26l1

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All Sequences

48
RefSeq

2
UniProt

1
CCDS

CCDS36187.1

Ensembl

ENSMUSG00000060938 (Evidence)
NCBI Gene

19941

			Length	Strain/Species	Flank
genomic	19941	NCBI Gene Model \| MGI Sequence Detail	2969	C57BL/6J	± kb
transcript	NM_009080	RefSeq \| MGI Sequence Detail	564	C57BL/6
polypeptide	P61255	UniProt \| EBI \| MGI Sequence Detail	145	Not Applicable

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UniProt

1 Sequence
GlyGen

P61255 1 site, 1 O-linked glycan (1 site)

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All nucleic 16

cDNA 14

Primer pair 2

Microarray probesets 4

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MGD-MRK-33704

Summaries

All 39

Developmental Gene Expression 4

Gene Ontology 9

Phenotypes 9
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731

TSS for Rpl26:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr102348	Chr11:68792343-68792355 (+)	-43 bp
Tssr102349	Chr11:68792364-68792459 (+)	20 bp
Tssr102350	Chr11:68792469-68792483 (+)	84 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24