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Gucy2g Gene Detail
Summary
  • Symbol
    Gucy2g
  • Name
    guanylate cyclase 2g
  • Synonyms
    2410077I05Rik, GC-G
  • Feature Type
    protein coding gene
  • IDs
    MGI:106025
    NCBI Gene: 73707
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:55186531-55229668 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 19, 51.18 cM, cytoband D2
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1594 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106025
protein coding gene Chr19:55186531-55229684 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025256
protein coding gene Chr19:55461453-55504774 (-)
A/J MGP_AJ_G0025232
protein coding gene Chr19:52737022-52781219 (-)
AKR/J MGP_AKRJ_G0025201
protein coding gene Chr19:54398628-54445598 (-)
BALB/cJ MGP_BALBcJ_G0025227
protein coding gene Chr19:52806822-52852273 (-)
C3H/HeJ MGP_C3HHeJ_G0024987
protein coding gene Chr19:54623953-54668988 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025670
protein coding gene Chr19:56832036-56876643 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023082
protein coding gene Chr19:51667689-51709796 (-)
CAST/EiJ MGP_CASTEiJ_G0024452
protein coding gene Chr19:54615948-54661875 (-)
CBA/J MGP_CBAJ_G0024967
protein coding gene Chr19:59623095-59675316 (-)
DBA/2J MGP_DBA2J_G0025099
protein coding gene Chr19:52532691-52575660 (-)
FVB/NJ MGP_FVBNJ_G0025060
protein coding gene Chr19:52235452-52278480 (-)
LP/J MGP_LPJ_G0025185
protein coding gene Chr19:55336637-55381546 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025093
protein coding gene Chr19:58999200-59042795 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025728
protein coding gene Chr19:54604224-54650224 (-)
PWK/PhJ MGP_PWKPhJ_G0024200
protein coding gene Chr19:52459894-52505343 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024003
protein coding gene Chr19:53281052-53324962 (-)
WSB/EiJ MGP_WSBEiJ_G0024522
protein coding gene Chr19:54727932-54774696 (-)



Homology
more
  • Human Ortholog
    GUCY2GP, guanylate cyclase 2G, pseudogene
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GUCY2GP, guanylate cyclase 2G, pseudogene
  • Synonyms
    GUCY2G
  • Links
    NCBI Gene ID: 390003

  • Chr Location
    10q25.2; chr10:112308178-112356595 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation are viable and fertile with no gross abnormalities and are protected against acute ischemia induced renal injury.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000055523 Ensembl Gene Model | MGI Sequence Detail 43138 C57BL/6J ±  kb
transcript ENSMUST00000069183 Ensembl | MGI Sequence Detail 3888 Not Applicable  
polypeptide ENSMUSP00000068253 Ensembl | MGI Sequence Detail 1100 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 4
    Primer pair 3

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-33707, MGI:1920957
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:31346 Yang RB, et al., Chromosomal localization and genomic organization of genes encoding guanylyl cyclase receptors expressed in olfactory sensory neurons and retina. Genomics. 1996 Feb 1;31(3):367-72
  • Latest
    J:258316 Chao YC, et al., Guanylyl cyclase-G is an alarm pheromone receptor in mice. EMBO J. 2018 Jan 4;37(1):39-49

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory