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Cyp3a16 Gene Detail
Summary
  • Symbol
    Cyp3a16
  • Name
    cytochrome P450, family 3, subfamily a, polypeptide 16
  • Feature Type
    protein coding gene
  • IDs
    MGI:106099
    NCBI Gene: 13114
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr5:145373119-145406533 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 85.17 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    801 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106099
 protein coding gene Chr5:145373119-145406550 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030367
 protein coding gene Chr5:150876516-151028204 (-)
A/J MGP_AJ_G0030338
 protein coding gene Chr5:144398182-144472787 (-)
AKR/J MGP_AKRJ_G0030270
 protein coding gene Chr5:148896601-148935557 (-)
BALB/cJ MGP_BALBcJ_G0030353
 protein coding gene Chr5:145670644-145699126 (-)
C3H/HeJ MGP_C3HHeJ_G0030066
 protein coding gene Chr5:149739508-149815317 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030798
 protein coding gene Chr5:156393229-156427204 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0030034
 protein coding gene Chr5:162825861-162862090 (-)
DBA/2J MGP_DBA2J_G0030185
 protein coding gene Chr5:144115166-144320702 (-)
FVB/NJ MGP_FVBNJ_G0030141
 protein coding gene Chr5:143353199-143392961 (-)
LP/J MGP_LPJ_G0030274
 protein coding gene Chr5:151510517-151550173 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030173
 protein coding gene Chr5:165162599-165195798 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030840
 protein coding gene Chr5:148815517-149100875 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CYP3A5, cytochrome P450 family 3 subfamily A member 5
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP3A5, cytochrome P450 family 3 subfamily A member 5
  • Synonyms
    CP35, CYPIIIA5, P450PCN3, PCN3
  • Links
    NCBI Gene ID: 1577
    neXtProt AC: NX_P20815
    UniProt: P20815

  • Chr Location
    7q22.1; chr7:99648194-99679996 (-)  GRCh38
Human Diseases
more
  • Diseases
    5 with human CYP3A4,CYP3A5 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    20 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    735
  • Tissues
    16
  • cDNA Data
    3
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038656 Ensembl Gene Model | MGI Sequence Detail 33415 C57BL/6J ±  kb
transcript ENSMUST00000031633 Ensembl | MGI Sequence Detail 1730 Not Applicable  
polypeptide ENSMUSP00000031633 Ensembl | MGI Sequence Detail 504 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    Genomic 6
    cDNA 3
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-33786
References
more
  • Summaries
    All 44
    Developmental Gene Expression 4
    Gene Ontology 7
    Phenotypes 20
  • Earliest
    J:22655 Itoh S, et al., A novel form of mouse cytochrome P450 3A (Cyp3a-16). Its cDNA cloning and expression in fetal liver. Eur J Biochem. 1994 Dec 15;226(3):877-82
  • Latest
    J:345093 Heintz MM, et al., Human CYP2B6 produces oxylipins from polyunsaturated fatty acids and reduces diet-induced obesity. PLoS One. 2022;17(12):e0277053
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory