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Trim36 Gene Detail
Summary
  • Symbol
    Trim36
  • Name
    tripartite motif-containing 36
  • Synonyms
    D18Wsu100e, Haprin
  • Feature Type
    protein coding gene
  • IDs
    MGI:106264
    NCBI Gene: 28105
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:46298367-46345674 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 24.41 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1377 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106264
 protein coding gene Chr18:46298367-46345674 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024404
 protein coding gene Chr18:44952042-45001658 (-)
A/J MGP_AJ_G0024371
 protein coding gene Chr18:43327816-43375131 (-)
AKR/J MGP_AKRJ_G0024340
 protein coding gene Chr18:44524675-44571611 (-)
BALB/cJ MGP_BALBcJ_G0024371
 protein coding gene Chr18:43444491-43490876 (-)
C3H/HeJ MGP_C3HHeJ_G0024138
 protein coding gene Chr18:44605532-44657171 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024815
 protein coding gene Chr18:46525879-46575135 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022250
 protein coding gene Chr18:43176897-43225483 (-)
CAST/EiJ MGP_CASTEiJ_G0023612
 protein coding gene Chr18:44568158-44621828 (-)
CBA/J MGP_CBAJ_G0024107
 protein coding gene Chr18:47779479-47831647 (-)
DBA/2J MGP_DBA2J_G0024237
 protein coding gene Chr18:42934073-43003569 (-)
FVB/NJ MGP_FVBNJ_G0024203
 protein coding gene Chr18:42522693-42568026 (-)
LP/J MGP_LPJ_G0024321
 protein coding gene Chr18:45000969-45052388 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024234
 protein coding gene Chr18:49146739-49195741 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024862
 protein coding gene Chr18:44433898-44484848 (-)
PWK/PhJ MGP_PWKPhJ_G0023356
 protein coding gene Chr18:43086072-43134408 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023161
 protein coding gene Chr18:44589802-44643788 (-)
WSB/EiJ MGP_WSBEiJ_G0023675
 protein coding gene Chr18:44322246-44376369 (-)



Homology
more
  • Human Ortholog
    TRIM36, tripartite motif containing 36
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIM36, tripartite motif containing 36
  • Synonyms
    ANPH, ANPH1, HAPRIN, RBCC728, RNF98
  • Links
    NCBI Gene ID: 55521
    neXtProt AC: NX_Q9NQ86
    UniProt: Q9NQ86

  • Chr Location
    5q22.3; chr5:115124762-115180546 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human TRIM36 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice for a null allele exhibit normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    24
  • cDNA Data
    23
  • Literature Summary
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 28105 NCBI Gene Model | MGI Sequence Detail 47308 C57BL/6J ±  kb
    transcript NM_178872 RefSeq | MGI Sequence Detail 4556 ZRU/MplStud  
    polypeptide Q80WG7 UniProt | EBI | MGI Sequence Detail 729 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 25
      cDNA 23
      Primer pair 2

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-33956
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 8
      Gene Ontology 8
      Phenotypes 10
    • Earliest
      J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
    • Latest
      J:348435 Suzuki A, et al., Individual disruption of 12 testis-enriched genes via the CRISPR/Cas9 system does not affect the fertility of male mice. J Reprod Immunol. 2024;:104252
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory