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Mapre2 Gene Detail
Summary
  • Symbol
    Mapre2
  • Name
    microtubule-associated protein, RP/EB family, member 2
  • Synonyms
    C820009F03Rik, D18Abb1e, EB2, RP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:106271
    NCBI Gene: 212307
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:23885390-24026918 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 12.08 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3859 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106271
 protein coding gene Chr18:23885390-24026918 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024193
 protein coding gene Chr18:21462923-21599530 (+)
A/J MGP_AJ_G0024158
 protein coding gene Chr18:20889532-21025297 (+)
AKR/J MGP_AKRJ_G0024127
 protein coding gene Chr18:21527605-21665265 (+)
BALB/cJ MGP_BALBcJ_G0024158
 protein coding gene Chr18:20937355-21071617 (+)
C3H/HeJ MGP_C3HHeJ_G0023926
 protein coding gene Chr18:21438922-21582144 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024600
 protein coding gene Chr18:22397227-22537577 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022042
 protein coding gene Chr18:20757348-20893036 (+)
CAST/EiJ MGP_CASTEiJ_G0023400
 protein coding gene Chr18:21239301-21374945 (+)
CBA/J MGP_CBAJ_G0023894
 protein coding gene Chr18:22993014-23131947 (+)
DBA/2J MGP_DBA2J_G0024026
 protein coding gene Chr18:20564526-20702345 (+)
FVB/NJ MGP_FVBNJ_G0023992
 protein coding gene Chr18:20314319-20448599 (+)
LP/J MGP_LPJ_G0024107
 protein coding gene Chr18:21637234-21777140 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024020
 protein coding gene Chr18:24031251-24165175 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024648
 protein coding gene Chr18:21273887-21422402 (+)
PWK/PhJ MGP_PWKPhJ_G0023144
 protein coding gene Chr18:20691150-20834087 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022953
 protein coding gene Chr18:21503844-21639958 (+)
WSB/EiJ MGP_WSBEiJ_G0023464
 protein coding gene Chr18:21182839-21318199 (+)



Homology
more
  • Human Ortholog
    MAPRE2, microtubule associated protein RP/EB family member 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAPRE2, microtubule associated protein RP/EB family member 2
  • Synonyms
    CSCSC2, EB1, EB2, RP1
  • Links
    NCBI Gene ID: 10982
    neXtProt AC: NX_Q15555
    UniProt: Q15555

  • Chr Location
    18q12.1-q12.2; chr18:34976928-35143470 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human MAPRE2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    827
  • Tissues
    14
  • cDNA Data
    192
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 212307 NCBI Gene Model | MGI Sequence Detail 141529 C57BL/6J ±  kb
transcript NM_153058 RefSeq | MGI Sequence Detail 4044 ZRU/MplStud  
polypeptide Q8R001 UniProt | EBI | MGI Sequence Detail 326 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 195
    cDNA 194
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-33963, MGI:2147206, MGI:2442212
References
more
  • Summaries
    All 40
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:34960 Chambers DM, et al., Isolation and mapping of novel mouse brain cDNA clones containing trinucleotide repeats, and demonstration of novel alleles in recombinant inbred strains. Genome Res. 1996 Aug;6(8):715-23
  • Latest
    J:263382 Yue J, et al., Microtubules regulate focal adhesion dynamics through MAP4K4. Dev Cell. 2014 Dec 8;31(5):572-85
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory