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Atp5po Gene Detail
Summary
  • Symbol
    Atp5po
  • Name
    ATP synthase peripheral stalk subunit OSCP
  • Synonyms
    Atp5o, D12Wsu28e
  • Feature Type
    protein coding gene
  • IDs
    MGI:106341
    NCBI Gene: 28080
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:91722111-91728518 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 53.26 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    371 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106341
 protein coding gene Chr16:91481286-91728575 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023048
 protein coding gene Chr16:92714908-92983914 (-)
A/J MGP_AJ_G0023016
 protein coding gene Chr16:88378450-88632192 (-)
AKR/J MGP_AKRJ_G0022986
 protein coding gene Chr16:91047385-91311796 (-)
BALB/cJ MGP_BALBcJ_G0023018
 protein coding gene Chr16:88905540-89154596 (-)
C3H/HeJ MGP_C3HHeJ_G0022779
 protein coding gene Chr16:91623667-91878864 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023465
 protein coding gene Chr16:95706734-95959748 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020967
 protein coding gene Chr16:86075563-86323151 (-)
CAST/EiJ MGP_CASTEiJ_G0022298
 protein coding gene Chr16:92185545-92450369 (-)
CBA/J MGP_CBAJ_G0022748
 protein coding gene Chr16:99797056-100067854 (-)
DBA/2J MGP_DBA2J_G0022882
 protein coding gene Chr16:88282424-88539697 (-)
FVB/NJ MGP_FVBNJ_G0022856
 protein coding gene Chr16:87406977-87667621 (-)
LP/J MGP_LPJ_G0022952
 protein coding gene Chr16:92412304-92670929 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022877
 protein coding gene Chr16:104341096-104602257 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023483
 protein coding gene Chr16:91569601-91827057 (-)
PWK/PhJ MGP_PWKPhJ_G0022043
 protein coding gene Chr16:88461030-88712988 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021873
 protein coding gene Chr16:91130674-91393643 (-)
WSB/EiJ MGP_WSBEiJ_G0022350
 protein coding gene Chr16:91811541-92073867 (-)



Homology
more
  • Human Ortholog
    ATP5PO, ATP synthase peripheral stalk subunit OSCP
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATP5PO, ATP synthase peripheral stalk subunit OSCP
  • Synonyms
    ATP5O, ATPO, HMC08D05, MC5DN7, OSCP
  • Links
    NCBI Gene ID: 539
    neXtProt AC: NX_P48047
    UniProt: P48047

  • Chr Location
    21q22.11; chr21:33903453-33915814 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human ATP5PO associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    4 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    78 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    217
  • Tissues
    170
  • cDNA Data
    326
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 28080 NCBI Gene Model | MGI Sequence Detail 6408 C57BL/6J ±  kb
transcript NM_138597 RefSeq | MGI Sequence Detail 772 C57BL/6  
polypeptide Q9DB20 UniProt | EBI | MGI Sequence Detail 213 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000004465 ATP synthase subunit O, mitochondrial
    (term hierarchy)
  • InterPro Domains
    IPR000711 ATPase, OSCP/delta subunit
    IPR020781 ATPase, OSCP/delta subunit, conserved site
    IPR024861 Donson
    IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily
  • GlyGen
    Q9DB20 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 329
    cDNA 326
    Primer pair 2
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-34033, MGI:7469653
References
more
  • Summaries
    All 122
    Developmental Gene Expression 7
    Diseases 4
    Gene Ontology 10
    Phenotypes 78
  • Earliest
    J:42265 Huang TT, et al., Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts. Arch Biochem Biophys. 1997 Aug 15;344(2):424-32
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory