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Zmiz2 Gene Detail
Summary
  • Symbol
    Zmiz2
  • Name
    zinc finger, MIZ-type containing 2
  • Synonyms
    2410117E06Rik, D11Bwg0280e, Zimp7
  • Feature Type
    protein coding gene
  • IDs
    MGI:106374
    NCBI Gene: 52915
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:6339074-6356158 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 3.95 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    343 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106374
 protein coding gene Chr11:6339063-6356158 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018021
 protein coding gene Chr11:3501611-3519714 (+)
A/J MGP_AJ_G0017994
 protein coding gene Chr11:3356099-3373178 (+)
AKR/J MGP_AKRJ_G0017958
 protein coding gene Chr11:3522317-3539402 (+)
BALB/cJ MGP_BALBcJ_G0017962
 protein coding gene Chr11:3362325-3379388 (+)
C3H/HeJ MGP_C3HHeJ_G0017775
 protein coding gene Chr11:3396209-3413699 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018414
 protein coding gene Chr11:3606091-3624797 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016072
 protein coding gene Chr11:3245582-3262702 (+)
CAST/EiJ MGP_CASTEiJ_G0017337
 protein coding gene Chr11:3380853-3397909 (+)
CBA/J MGP_CBAJ_G0017750
 protein coding gene Chr11:4011047-4028198 (+)
DBA/2J MGP_DBA2J_G0017860
 protein coding gene Chr11:3267864-3284967 (+)
FVB/NJ MGP_FVBNJ_G0017852
 protein coding gene Chr11:3289960-3309097 (+)
LP/J MGP_LPJ_G0017931
 protein coding gene Chr11:3578612-3595675 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017878
 protein coding gene Chr11:3562060-3579752 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018454
 protein coding gene Chr11:3544552-3561593 (+)
PWK/PhJ MGP_PWKPhJ_G0017117
 protein coding gene Chr11:3300170-3317644 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016914
 protein coding gene Chr11:3481386-3499409 (+)
WSB/EiJ MGP_WSBEiJ_G0017391
 protein coding gene Chr11:3363259-3380981 (+)



Homology
more
  • Human Ortholog
    ZMIZ2, zinc finger MIZ-type containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZMIZ2, zinc finger MIZ-type containing 2
  • Synonyms
    hZIMP7, NET27, TRAFIP20, ZIMP7
  • Links
    NCBI Gene ID: 83637
    neXtProt AC: NX_Q8NF64
    UniProt: Q8NF64

  • Chr Location
    7p13; chr7:44748571-44769881 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1076
  • Tissues
    158
  • cDNA Data
    100
  • Literature Summary
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041164 Ensembl Gene Model | MGI Sequence Detail 17085 C57BL/6J ±  kb
transcript ENSMUST00000109787 Ensembl | MGI Sequence Detail 4116 Not Applicable  
polypeptide ENSMUSP00000105410 Ensembl | MGI Sequence Detail 920 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 103
    cDNA 100
    Primer pair 3

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-34067, MGI:1920928, MGI:2144700
References
more
  • Summaries
    All 44
    Developmental Gene Expression 10
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory