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Prm3 Gene Detail
Summary
  • Symbol
    Prm3
  • Name
    protamine 3
  • Synonyms
    PX, Pxg, Pxg
  • Feature Type
    protein coding gene
  • IDs
    MGI:106601
    NCBI Gene: 19120
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:10608372-10608778 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 5.84 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    83 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106601
 protein coding gene Chr16:10608369-10608778 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022513
 protein coding gene Chr16:7617865-7618277 (-)
A/J MGP_AJ_G0022475
 protein coding gene Chr16:7200302-7200711 (-)
AKR/J MGP_AKRJ_G0022451
 protein coding gene Chr16:7520453-7520862 (-)
BALB/cJ MGP_BALBcJ_G0022479
 protein coding gene Chr16:7330961-7331370 (-)
C3H/HeJ MGP_C3HHeJ_G0022246
 protein coding gene Chr16:7605652-7606058 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022928
 protein coding gene Chr16:7765297-7765706 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020449
 protein coding gene Chr16:7346352-7346764 (-)
CAST/EiJ MGP_CASTEiJ_G0021773
 protein coding gene Chr16:7624781-7625190 (-)
CBA/J MGP_CBAJ_G0022215
 protein coding gene Chr16:8117032-8117438 (-)
DBA/2J MGP_DBA2J_G0022346
 protein coding gene Chr16:7203484-7203890 (-)
FVB/NJ MGP_FVBNJ_G0022322
 protein coding gene Chr16:7185853-7186262 (-)
LP/J MGP_LPJ_G0022414
 protein coding gene Chr16:7570179-7570591 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022344
 protein coding gene Chr16:7825301-7825710 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022941
 protein coding gene Chr16:7475967-7476376 (-)
PWK/PhJ MGP_PWKPhJ_G0021513
 protein coding gene Chr16:7412338-7412747 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021343
 protein coding gene Chr16:7534062-7534471 (-)
WSB/EiJ MGP_WSBEiJ_G0021821
 protein coding gene Chr16:7554577-7554986 (-)



Homology
more
  • Human Ortholog
    PRM3, protamine 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRM3, protamine 3
  • Links
    NCBI Gene ID: 58531
    neXtProt AC: NX_Q9NNZ6
    UniProt: Q9NNZ6

  • Chr Location
    16p13.13; chr16:11273199-11273629 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Males that are null homozygous for this gene have reduced sperm motility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    13
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 19120 NCBI Gene Model | MGI Sequence Detail 407 C57BL/6J ±  kb
transcript NM_013638 RefSeq | MGI Sequence Detail 407 ZRU/MplStud  
polypeptide Q62100 UniProt | EBI | MGI Sequence Detail 101 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    Genomic 2
    cDNA 14

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-35057, MGI:3039637
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:43871 Schluter G, et al., The rat Prm3 gene is an intronless member of the protamine gene cluster and is expressed in haploid male germ cells. Cytogenet Cell Genet. 1995;71(4):352-5
  • Latest
    J:198562 Cantu C, et al., The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription. Development. 2013 Jun;140(11):2377-86
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory