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Cdh16 Gene Detail
Summary
  • Symbol
    Cdh16
  • Name
    cadherin 16
  • Synonyms
    KSP-cadherin
  • Feature Type
    protein coding gene
  • IDs
    MGI:106671
    NCBI Gene: 12556
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:105328547-105351028 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 53.04 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    630 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106671
 protein coding gene Chr8:105328543-105351028 (-)
129S1/SvImJ ENSMUSG00200014983
 protein coding gene Chr8:99626793-99648318 (-)
A/J ENSMUSG00195003916
 protein coding gene Chr8:99910293-99931820 (-)
AKR/J ENSMUSG00220011307
 protein coding gene Chr8:100077408-100098931 (-)
BALB/cJ ENSMUSG00180004005
 protein coding gene Chr8:99935694-99957223 (-)
C3H/HeJ ENSMUSG00175002595
 protein coding gene Chr8:99992466-100013989 (-)
C57BL/6NJ ENSMUSG00215001208
 protein coding gene Chr8:99606772-99628296 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031452
 protein coding gene Chr8:95794155-95804606 (-)
CAST/EiJ ENSTCUG00005022552
 protein coding gene Chr8:99391726-99414064 (-)
CBA/J ENSMUSG00210014970
 protein coding gene Chr8:99921070-99942593 (-)
DBA/2J ENSMUSG00185004927
 protein coding gene Chr8:106028940-106050463 (-)
FVB/NJ ENSMUSG00205012041
 protein coding gene Chr8:98953908-98975432 (-)
JF1/MsJ ENSUMUG00000012099
 protein coding gene Chr8:108362164-108383691 (-)
LP/J ENSMUSG00230006800
 protein coding gene Chr8:109709476-109730999 (-)
NOD/ShiLtJ ENSMUSG00190011977
 protein coding gene Chr8:100059131-100080656 (-)
NZO/HlLtJ ENSMUSG00225019419
 protein coding gene Chr8:113059974-113081497 (-)
PWK/PhJ ENSLUMG00010003862
 protein coding gene Chr8:99875752-99897880 (-)
SPRET/EiJ ENSMSPG00010040048
 protein coding gene Chr8:101992858-102016485 (-)
WSB/EiJ ENSIUOG00005005871
 protein coding gene Chr8:100739180-100760704 (-)



Homology
more
  • Human Ortholog
    CDH16, cadherin 16
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDH16, cadherin 16
  • Links
    NCBI Gene ID: 1014
    UniProt: O75309

  • Chr Location
    16q22.1; chr16:66908122-66919187 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    43
  • cDNA Data
    124
  • Literature Summary
    14
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 12556 NCBI Gene Model | MGI Sequence Detail 22482 C57BL/6J ±  kb
transcript NM_007663 RefSeq | MGI Sequence Detail 3025 ZRU/MplStud  
polypeptide O88338 UniProt | EBI | MGI Sequence Detail 830 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 126
    cDNA 124
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-35130
References
more
  • Summaries
    All 61
    Developmental Gene Expression 14
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:33452 Thomson RB, et al., Isolation and cDNA cloning of Ksp-cadherin, a novel kidney-specific member of the cadherin multigene family. J Biol Chem. 1995 Jul 21;270(29):17594-601
  • Latest
    J:368965 Sun P, et al., Renal tubular S100A7a impairs fatty acid oxidation and exacerbates renal fibrosis via both intracellular and extracellular pathway. Biochim Biophys Acta Mol Basis Dis. 2025 Jan 6;1871(3):167656
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory