Tmem191 MGI Mouse Gene Detail - MGI:107238

Symbol

Tmem191
Name

transmembrane protein 191
Synonyms

4933405M22Rik, D16Bwg1494e, MNCb-4137, Tmem191c

Feature Type

protein coding gene
IDs

MGI:107238
NCBI Gene: 224019
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr16:17094164-17096525 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 16, 10.71 cM
Mapping Data

3 experiments

SNPs within 2kb

117 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_107238	protein coding gene	Chr16:17093941-17101093 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0022576	protein coding gene	Chr16:14415019-14421936 (+)
A/J	MGP_AJ_G0022537	protein coding gene	Chr16:13698981-13705943 (+)
AKR/J	MGP_AKRJ_G0022514	protein coding gene	Chr16:14245108-14252075 (+)
BALB/cJ	MGP_BALBcJ_G0022540	protein coding gene	Chr16:13844075-13851044 (+)
C3H/HeJ	MGP_C3HHeJ_G0022307	protein coding gene	Chr16:14381482-14388399 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0022991	protein coding gene	Chr16:14646118-14653028 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0020511	protein coding gene	Chr16:13774584-13781743 (+)
CAST/EiJ	MGP_CASTEiJ_G0021835	protein coding gene	Chr16:14289943-14296926 (+)
CBA/J	MGP_CBAJ_G0022278	protein coding gene	Chr16:15321881-15328795 (+)
DBA/2J	MGP_DBA2J_G0022408	protein coding gene	Chr16:13624240-13631185 (+)
FVB/NJ	MGP_FVBNJ_G0022384	protein coding gene	Chr16:13666317-13673298 (+)
LP/J	MGP_LPJ_G0022475	protein coding gene	Chr16:14176492-14183412 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0022405	protein coding gene	Chr16:14996755-15008092 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0023002	protein coding gene	Chr16:14178534-14185452 (+)
PWK/PhJ	MGP_PWKPhJ_G0021578	protein coding gene	Chr16:13869131-13876155 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0021406	protein coding gene	Chr16:14164939-14171919 (+)
WSB/EiJ	MGP_WSBEiJ_G0021882	protein coding gene	Chr16:14182968-14189921 (+)

Human Ortholog

TMEM191B, transmembrane protein 191B

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TMEM191B, transmembrane protein 191B
Links

HGNC:33600

NCBI Gene ID: 728229

neXtProt AC: NX_P0C7N4

UniProt: P0C7N4
Chr Location

22q11.21; chr22:18527802-18530573 (+) GRCh38

Human Ortholog

TMEM191C, transmembrane protein 191C
Links

HGNC:33601

NCBI Gene ID: 645426

neXtProt AC: NX_A6NGB0

UniProt: A6NGB0
Chr Location

22q11.21; chr22:21466423-21471269 (+) GRCh38

MGI Vertebrate Homology

Tmem191 stringent orthology
2 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: TMEM191B, TMEM191C
Gene Tree

Tmem191

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Phenotype Summary

5 phenotype references

All Mutations and Alleles

4
Endonuclease-mediated

2
Targeted

2
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

18 strains or lines available

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All GO Annotations

1
GO References

1

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

27

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

54
RefSeq

2
UniProt

4
CCDS

CCDS49776.1

Ensembl

ENSMUSG00000055692 (Evidence)
NCBI Gene

224019

			Length	Strain/Species	Flank
genomic	224019	NCBI Gene Model \| MGI Sequence Detail	2362	C57BL/6J	± kb
transcript	NM_177473	RefSeq \| MGI Sequence Detail	1463	C57BL/6
polypeptide	Q9JJB1	UniProt \| EBI \| MGI Sequence Detail	302	Not Applicable

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UniProt

4 Sequences
InterPro Domains

IPR028186 Transmembrane protein 191B/C

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All nucleic 30

Genomic 2

cDNA 27

Primer pair 1

Microarray probesets 6

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MGD-MRK-35703, MGI:1921313, MGI:7286476

Summaries

All 28

Gene Ontology 1

Phenotypes 5
Earliest

J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
Latest

J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

TSS for Tmem191:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr137285	Chr16:17094155-17094194 (+)	11 bp
Tssr137286	Chr16:17094201-17094222 (+)	48 bp
Tssr137287	Chr16:17094526-17094544 (+)	371 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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