Tsil Gene Detail

Summary

• Symbol
  Tsil
• Name
  thymus specific insertion locus

• Feature Type
  unclassified gene
• IDs
  MGI:107442
  NCBI Gene: 110217
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 17, Syntenic
• Mapping Data
  3 experiments

Strain
Comparison

• PCR
  1

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotypes from multigenic genotypes
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Transgenic
  1
• Find Mice (IMSR)
  0 strains or lines available

Mice homozygous for a transgene insertion display an increased thymic CD4+ CD8+ population and die prematurely prior to tumor development; about 50% of heterozygous mice develop T cell lymphomas at 2-5 months of age.

Expression

• Assay Results
  6
• Tissues
  4
• Literature Summary
  1

Tissue x Stage Matrix

Sequences &
Gene Models

• NCBI Gene
  110217

Molecular
Reagents

• All nucleic 6

  Genomic 5

  Primer pair 1

Other
Accession IDs

MGD-MRK-35913

References

• Summaries
  All 2

  Developmental Gene Expression 1

  Phenotypes 1
• Earliest
  J:33857 Lavenu A, et al., Genomic structure and precise mapping of a thymic regulatory region on mouse chromosome 17 revealed by a c-myc transgene insertion. Genomics. 1996 Jun 15;34(3):381-8