Fts Gene Detail

Summary

• Symbol
  Fts
• Name
  fused toes
• Synonyms
  Ft

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:107456
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr8:91632145-93455280 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 8, cytoband D
• Mapping Data
  5 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  34 phenotypes from 1 allele in 4 genetic backgrounds
  12 phenotype references
  

• All Mutations and Alleles
  1
• Transgenic
  1
• Find Mice (IMSR)
  0 strains or lines available

Mice heterozygous for a deletion caused by transgenic insertional mutagenesis show syndactyly, thymic hyperplasia, and altered thymopoiesis. Homozygotes die by E13.5 showing craniofacial defects, digit anomalies, and abnormal left-right axis formation, brain development, and germ cell proliferation.

Other
Accession IDs

MGD-MRK-35927, MGI:2142660

References

• Summaries
  All 15

  Phenotypes 12
• Earliest
  J:20159 van der Hoeven F, et al., Programmed cell death is affected in the novel mouse mutant Fused toes (Ft). Development. 1994 Sep;120(9):2601-7
• Latest
  J:173702 Kim B, et al., The fused toes locus is essential for somatic-germ cell interactions that foster germ cell maturation in developing gonads in mice. Biol Reprod. 2011 May;84(5):1024-32