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Cox6b1 Gene Detail
Summary
  • Symbol
    Cox6b1
  • Name
    cytochrome c oxidase, subunit 6B1
  • Synonyms
    2010000G05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:107460
    NCBI Gene: 110323
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:30316396-30325539 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 18.84 cM, cytoband A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    392 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107460
 protein coding gene Chr7:30316286-30325576 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032034
 protein coding gene Chr7:29625953-29634909 (-)
A/J MGP_AJ_G0032011
 protein coding gene Chr7:28822468-28832242 (-)
AKR/J MGP_AKRJ_G0031944
 protein coding gene Chr7:29555698-29564699 (-)
BALB/cJ MGP_BALBcJ_G0032018
 protein coding gene Chr7:29012118-29021329 (-)
C3H/HeJ MGP_C3HHeJ_G0031737
 protein coding gene Chr7:30018533-30027828 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032484
 protein coding gene Chr7:30588996-30598439 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029534
 protein coding gene Chr7:29852722-29861540 (-)
CAST/EiJ MGP_CASTEiJ_G0031071
 protein coding gene Chr7:23269250-23279708 (-)
CBA/J MGP_CBAJ_G0031703
 protein coding gene Chr7:32045015-32056565 (-)
DBA/2J MGP_DBA2J_G0031855
 protein coding gene Chr7:28551461-28560773 (-)
FVB/NJ MGP_FVBNJ_G0031812
 protein coding gene Chr7:28682353-28691530 (-)
LP/J MGP_LPJ_G0031936
 protein coding gene Chr7:29932848-29942698 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031848
 protein coding gene Chr7:31279208-31289590 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032512
 protein coding gene Chr7:29066809-29077475 (-)
PWK/PhJ MGP_PWKPhJ_G0030795
 protein coding gene Chr7:23590471-23600347 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030630
 protein coding gene Chr7:20078973-20088012 (-)
WSB/EiJ MGP_WSBEiJ_G0031181
 protein coding gene Chr7:29455199-29464948 (-)



Homology
more
  • Human Ortholog
    COX6B1, cytochrome c oxidase subunit 6B1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COX6B1, cytochrome c oxidase subunit 6B1
  • Synonyms
    COX6B, COXG, COXVIb1, MC4DN7
  • Links
    NCBI Gene ID: 1340
    neXtProt AC: NX_P14854
    UniProt: P14854

  • Chr Location
    19q13.12; chr19:35648323-35658782 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human COX6B1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    817
  • Tissues
    104
  • cDNA Data
    330
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 110323 NCBI Gene Model | MGI Sequence Detail 9144 C57BL/6J ±  kb
    transcript NM_025628 RefSeq | MGI Sequence Detail 487 ZRU/MplStud  
    polypeptide P56391 UniProt | EBI | MGI Sequence Detail 86 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 333
      cDNA 332
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-35931, MGI:1913792
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 4
      Gene Ontology 7
      Phenotypes 9
    • Earliest
      J:34617 Stubbs L, et al., Detailed comparative map of human chromosome 19q and related regions of the mouse genome. Genomics. 1996 Aug 1;35(3):499-508
    • Latest
      J:355679 Vercellino I, et al., SCAF1 drives the compositional diversity of mammalian respirasomes. Nat Struct Mol Biol. 2024 Jul;31(7):1061-1071
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory