Ccw Gene Detail

Summary

• Symbol
  Ccw
• Name
  cataract and curly whiskers

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:107542
  NCBI Gene: 110045
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 4, Syntenic
• Mapping Data
  5 experiments

Human Diseases

• Diseases
  1 with Ccw mouse models

Human Disease

Mouse Models

cataract

IDs

cataract      

DOID:83
ICD10CM:H26
ICD9CM:366.8
OMIM:601371
OMIM:PS116200
UMLS_CUI:C0029531

View 1 model

Mouse Models

Human Disease Modeled: cataract

Allelic Composition	Genetic Background	Reference	Phenotypes
Ccw/Ccw+	involves: unpedigreed stock	J:34877 J:66649	View

Click on a disease name to see all genes associated with that disease.

• Mutations/Alleles
  1 with disease annotations

• References
  2 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotypes from 1 allele in 1 genetic background
  2 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  0 strains or lines available

Heterozygotes for a spontaneous mutation exhibit curly vibrissae, with a progressive, diffuse clouding of the lens evident by three weeks of age. Homozygotes die soon after implantation.

Sequences &
Gene Models

• NCBI Gene
  110045

Other
Accession IDs

MGD-MRK-36112

References

• Summaries
  All 4

  Diseases 2

  Phenotypes 2
• Earliest
  J:24877 Foulds L, Mammary tumours in hybrid mice: The presence and transmission of the mammary tumour agent. Br J Cancer. 1949;3(2):230-9
• Latest
  J:66649 Lyon MF, et al., Further genetic analysis of two autosomal dominant mouse eye defects, ccw and Pax6-coop. Mol Vis. 2000 Oct 31;6:199-203